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  • Lindberg, AnneUmeå universitet,Avdelningen för medicin (author)

Large underreporting of COPD as cause of death-results from a population-based cohort study

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • Elsevier BV,2021

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  • LIBRIS-ID:oai:gup.ub.gu.se/310316
  • https://gup.ub.gu.se/publication/310316URI
  • https://doi.org/10.1016/j.rmed.2021.106518DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-188956URI

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  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

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  • Background: In 2019, WHO estimated COPD to be the third leading cause of death in the world. However, COPD is probably underestimated as cause of death due to the well-known under-diagnosis. Aim: To evaluate the proportion of and factors associated with COPD recorded as cause of death in a long-term follow-up of a population-based COPD cohort. Methods: The study population includes all individuals (n = 551) with COPD defined as chronic airway obstruction (post-bronchodilator FEV1/FVC<0.70) + respiratory symptoms identified after re-examinations of four population-based cohorts. Mortality and underlying or contributing cause of death following ICD-10 classification were collected from the Swedish National Board of Health and Welfares register from date of examination in 2002-04 until 2016. Results: The study sample consisted of 32.3% GOLD 1, 55.9% GOLD 2, and 11.8% GOLD 3-4. The mean follow-up time was 10.3 (SD3.77) years and the cumulative mortality 45.0%. COPD (ICD-10 J43-J44) was recorded on 28.2% (n = 70) of the death certificates (11.1%, 25.7% and 57.1% by GOLD stage), whereof n = 35 had COPD recorded as underlying and n = 35 as contributing cause of death. To have COPD recorded as cause of death was independently associated with ex- and current smoking and a self-reported physician diagnosis of COPD, while male sex, overweight/obesity and higher FEV1% of predicted associated with the absence. Conclusions: COPD was largely underreported cause of death. Even among those with severe/very severe disease, COPD was only mentioned on 57.1% of the death certificates.

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  • Lindberg, L.Umeå universitet,Avdelningen för medicin (author)
  • Sawalha, Sami,1975-Umeå universitet,Avdelningen för medicin(Swepub:umu)sasa0131 (author)
  • Nilsson, Ulf,1974-Umeå universitet,Avdelningen för medicin(Swepub:umu)ulni0011 (author)
  • Stridsman, CarolineUmeå universitet,Avdelningen för medicin(Swepub:umu)cast0052 (author)
  • Lundbäck, Bo,1948Gothenburg University,Göteborgs universitet,Krefting Research Centre,Krefting Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden(Swepub:gu)xlunbo (author)
  • Backman, HelenaUmeå universitet,Avdelningen för hållbar hälsa(Swepub:umu)heaban01 (author)
  • Umeå universitetAvdelningen för medicin (creator_code:org_t)

Related titles

  • In:Respiratory Medicine: Elsevier BV1860954-61111532-3064

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