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Review on pediatric coeliac disease from a clinical perspective
- Wessels, M. (author)
- Auricchio, R. (author)
- Dolinsek, J. (author)
- show more...
- Donat, E. (author)
- Gillett, P. (author)
- Meijer, C. (author)
- Popp, A. (author)
- Mearin, M. L. (author)
- show less...
- (creator_code:org_t)
- 2022-01-15
- 2022
- English.
- In: European Journal of Pediatrics. - : Springer Science and Business Media LLC. - 0340-6199 .- 1432-1076. ; 181:5, s. 1785-1795
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Coeliac disease is an immune-mediated condition characterized by chronic inflammation of the small bowel with villous atrophy driven by gluten ingestion in genetically predisposed individuals. It occurs frequently in both children and adults, affecting 1-4% of the population. The disease is associated with both gastrointestinal and extra-intestinal symptoms related to malabsorption and/or immune activation, and autoantibodies to tissue transglutaminase. Removal of gluten from the diet results in resolution of symptoms and enteropathy in the majority of patients. A good diagnostic work-up is important to avoid unnecessary restrictive diets in children. In this review on pediatric coeliac disease, we address epidemiology including predisposing environmental factors and possible preventive strategies, as well as the clinical presentation, diagnosis and follow-up.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Coeliac disease
- Children and adolescents
- Epidemiology
- Diagnosis
- Follow-up
- gluten-free diet
- quality-of-life
- autoimmune thyroid-disease
- increased
- prevalence
- larazotide acetate
- villous atrophy
- children
- risk
- infection
- diagnosis
- Pediatrics
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Wessels, M.
- Auricchio, R.
- Dolinsek, J.
- Donat, E.
- Gillett, P.
- Mårild, Karl, 19 ...
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- Meijer, C.
- Popp, A.
- Mearin, M. L.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Pediatrics
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- European Journal ...
- By the university
- University of Gothenburg
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