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The Role of Titaniu...
The Role of Titanium Particles and Ions in the Pathogenesis of Peri-Implantitis
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- Asa'ad, Farah, 1983 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Odontology,Institute of Clinical Sciences, Department of Biomaterials
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- Thomsen, Peter, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Ferreria Kunrath, Marcel, 1988 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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(creator_code:org_t)
- Korean Society for Bone and Mineral Research, 2022
- 2022
- English.
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In: Journal of Bone Metabolism. - : Korean Society for Bone and Mineral Research. - 2287-6375 .- 2287-7029. ; 29:3, s. 145-154
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Abstract
Subject headings
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- Titanium (Ti) particles and ions have been investigated in recent years as important factors in the pathogenesis of peri-implantitis. However, their role in the pathogenesis is yet to be fully understood. A review of pertinent literature was performed in various databases to determine the current position of Ti particles and ions role in the pathogenesis of peri-implantitis. There are several in vitro, preclinical and clinical published studies that have addressed the role of Ti particles and ions in the pathogenesis of peri-implantitis. These studies explored the effect of Ti particles and ions in the pathogenesis of peri-implantitis with respect to foreign body reaction, cellular response, epigenetic mechanisms, namely DNA methylation, and the oral microbiome. Studies have shown that the release of Ti particles/ions during implant insertion, early healing stages, late healing stages, and treatments during peri-implantitis might contribute to peri-implantitis through different mechanisms, such as foreign body reaction, cellular response, DNA methylation, and shaping the oral microbiome by increasing dysbiosis. However, further studies are needed to elucidate the complex interactions between all these mechanisms and Ti particles/ions in the pathogenesis and progression of peri-implantitis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- Dental implants · DNA methylation · Foreign-body reaction · Microbiota · Peri-implantitis · Titanium
Publication and Content Type
- ref (subject category)
- art (subject category)
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