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Muscle Function Tests as Supportive Outcome Measures for Performance-Based and Self-Reported Physical Function in Patients With Knee Osteoarthritis: Exploratory Analysis of Baseline Data From a Randomized Trial

Holm, P. M. (author)
Kemnitz, J. (author)
Bandholm, T. (author)
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Wernbom, Mathias, 1968 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kost- och idrottsvetenskap,Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering,Department of Food and Nutrition, and Sport Science,Institute of Neuroscience and Physiology, Department of Health and Rehabilitation
Schroder, H. M. (author)
Skou, S. T. (author)
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 (creator_code:org_t)
2022
2022
English.
In: Journal of Strength and Conditioning Research. - 1064-8011. ; 36:9, s. 2635-2642
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Uncertainty on the role of muscle function in relation to physical function in knee osteoarthritis (KOA) persists. This study aimed to assess the associations between muscle function and performance-based and self-reported physical function in patients with KOA. Physical function in 80 subjects with symptomatic and radiographic KOA was assessed using 40-m fast-paced walk, 30-second chair stand, 9-step stair climb tests, and the subscale activities of daily living from the Knee injury and Osteoarthritis Outcome Score (KOOS-ADL). Measurements of muscle function included leg extension (LE) power, knee extension (KE) torque, and estimated leg press one repetition maximum (LP RM). Associations were investigated using multivariable hierarchical linear regressions adjusted for age, sex, body mass index, self-reported physical activity, and thigh muscle lean area. Leg extension power was significantly associated with 40-m walk, stair climb, and 30-second chair stand, explaining 18, 8, and 3% of additional variance, respectively. Knee extension torque explained 13, 7, 17, and 7% of additional variance in the 40-m walk, stair climb, 30-second chair stand, and KOOS-ADL, respectively. Leg press one repetition maximum explained 11% of additional variance in the 30-second chair stand. In conclusion, LE power was the best explanatory variable for performance on the 40-m walk and stair climb tests, whereas KE torque best explained chair stand performance. Only KE torque was associated with KOOS-ADL. Our results highlight the importance of selecting supportive muscle function tests based on the specific physical function and suggest that other factors may be more important for certain physical function outcomes.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)

Keyword

strength
power
association
extension strength
older-adults
leg-press
power
quadriceps
people
arthroplasty
ability
hip
determinant
Sport Sciences

Publication and Content Type

ref (subject category)
art (subject category)

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Holm, P. M.
Kemnitz, J.
Bandholm, T.
Wernbom, Mathias ...
Schroder, H. M.
Skou, S. T.
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Health Sciences
and Sport and Fitnes ...
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Journal of Stren ...
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University of Gothenburg

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