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Results from the "M...
Results from the "Me & My Heart" (eMocial) Study: a Randomized Evaluation of a New Smartphone-Based Support Tool to Increase Therapy Adherence of Patients with Acute Coronary Syndrome
- Article/chapterEnglish2023
Publisher, publication year, extent ...
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2022-04-20
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Springer Science and Business Media LLC,2023
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/319047
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https://gup.ub.gu.se/publication/319047URI
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https://doi.org/10.1007/s10557-022-07331-1DOI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Purpose This study evaluated whether patient support, administered via an electronic device-based app, increased adherence to treatment and lifestyle changes in patients with acute coronary syndrome (ACS) treated with ticagrelor in routine clinical practice. Methods Patients (aged >= 18 years) with diagnosed ACS treated with ticagrelor co-administered with low-dose acetylsalicylic acid were randomized into an active group (with support tool app for medication intake reminders and motivational messages) and a control group (without support tool app), and observed for 48 weeks (ClinicalTrials.gov Identifier: NCT02615704). Patients were asked to complete the 36-item Short-Form Health Survey (SF-36) and Lifestyle Changes Questionnaire (LSQ), and were assessed for blood pressure and body mass index (BMI) at baseline (visit 1) and at the end of the study (visit 2). Medication adherence was measured using the Brilique Adherence Questionnaire (BAQ). Results Patients (N = 676) were randomized to an active (n = 342) or a control (n = 334) group. BAQ data were available for 174 patients in the active group and 174 patients in the control group. Over the 48-week period, mean (standard deviation) adherence for the active and control groups was 96.4% (13.2%) and 91.5% (23.1%), respectively (effect of app intervention, p < 0.05). There were no significant differences in blood pressure and BMI between visits. General improvements in SF-36 and LSQ scores were observed for both groups. Conclusion The patient support tool app was associated with significant improvements in patient-reported treatment adherence compared with a data collection app alone in patients prescribed ticagrelor for ACS.
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Jornten-Karlsson, M.
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Waliszewski, M.
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Knutsson, M.
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Niklasson, A.
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Appel, K. F.
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Degenhardt, R.
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Ghanem, A.
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Kohler, T.
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Ohlow, M. A.
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Tschope, C.
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Theres, H.
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vom Dahl, J.
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Karlson, Björn W.,1953Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xkabjo
(author)
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Maier, L. S.
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Göteborgs universitetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin
(creator_code:org_t)
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In:Cardiovascular Drugs and Therapy: Springer Science and Business Media LLC37:4, s. 729-7410920-32061573-7241
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Niklasson, A.
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Appel, K. F.
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Degenhardt, R.
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Ghanem, A.
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Kohler, T.
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Ohlow, M. A.
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Tschope, C.
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Theres, H.
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vom Dahl, J.
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