Diagnosis and management of hypertension in patients with Cushing's syndrome: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension

Endogenous/exogenous Cushing's syndrome is characterized by a cluster of systemic manifestations of hypercortisolism, which cause increased cardiovascular risk. Its biological basis is glucocorticoid excess, acting on various pathogenic processes inducing cardiovascular damage. Hypertension is a common feature in Cushing's syndrome and may persist after normalizing hormone excess and discontinuing steroid therapy. In endogenous Cushing's syndrome, the earlier the diagnosis the sooner management can be employed to offset the deleterious effects of excess cortisol. Such management includes combined treatments directed against the underlying cause and tailored antihypertensive drugs aimed at controlling the consequences of glucocorticoid excess. Experts on endocrine hypertension and members of the Working Group on Endocrine Hypertension of the European Society of Hypertension (ESH) prepared this Consensus document, which summarizes the current knowledge in epidemiology, genetics, diagnosis, and treatment of hypertension in Cushing's syndrome.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
adrenocorticotrophic hormone
adrenal cortex
cardiovascular
consensus
cortisol
Cushing
glucocorticoid
hypertension
pituitary
position
statement
blood-pressure profile
ectopic acth-secretion
adrenal incidentalomas
cardiovascular risk
clinical-practice
subclinical hypercortisolism
steroidogenesis inhibitors
genomic characterization
bilateral
adrenalectomy
differential-diagnosis
Cardiovascular System & Cardiology

Di Dalmazi, G. (author)
Beuschlein, F. (author)
Biermasz, N. R. (author)
Castinetti, F. (author)
Elenkova, A. (author)
Fassnacht, M. (author)
Isidori, A. M. (author)
Kastelan, D. (author)
Korbonits, M. (author)
Newell-Price, J. (author)
Parati, G. (author)
Petersenn, S. (author)
Pivonello, R. (author)
Ragnarsson, Oskar,1971Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xragos (author)
Tabarin, A. (author)
Theodoropoulou, M. (author)
Tsagarakis, S. (author)
Valassi, E. (author)
Witek, P. (author)
Reincke, M. (author)
Göteborgs universitetInstitutionen för medicin (creator_code:org_t)

In:Journal of hypertension: Ovid Technologies (Wolters Kluwer Health)40:11, s. 2085-21010263-63521473-5598

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Endocrinology an ...

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