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PSA: role in screen...
PSA: role in screening and monitoring patients with prostate cancer
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- Carlsson, Sigrid, 1982 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Sahlgrenska Academy,Memorial Sloan-Kettering Cancer Center
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- Murata, K. (author)
- Memorial Sloan-Kettering Cancer Center
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- Lilja, Hans (author)
- Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Clinical Chemistry, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Memorial Sloan-Kettering Cancer Center
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- Danila, D. C. (author)
- Memorial Sloan-Kettering Cancer Center
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(creator_code:org_t)
- 2022
- 2022
- English.
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In: Cancer Biomarkers: Clinical Aspects and Laboratory Determination. - 9780128243022 - 9780128243039 ; , s. 131-172
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Abstract
Subject headings
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- The test used for early detection and monitoring of prostate cancer—prostate-specific antigen (PSA)—is one of the most accurate and frequently used tumor markers in medicine today. No tumor marker has had such a critical impact on early detection through stage-migration, and monitoring after treatment for prostate cancer as the blood test PSA. This chapter provides an overview of the PSA test and its distinct molecular forms in blood, in screening, early detection and monitoring of prostate cancer. This chapter gives a summary of the randomized controlled trials of PSA-screening and recommendations from national guidelines groups. The chapter discusses the role of the PSA-test as a tool to discriminate clinically significant from indolent prostate cancer at prostate biopsy as well as the growing evidence regarding its role as a risk-stratification tool and prognostic marker of future lethal prostate cancer. © 2022 Elsevier Inc. All rights reserved.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Keyword
- biomarkers
- monitoring
- Prostate cancer
- prostate-specific antigen
- PSA
- screening
- treatment
Publication and Content Type
- vet (subject category)
- kap (subject category)
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