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Quantitative flow r...
Quantitative flow ratio versus fractional flow reserve for guiding percutaneous coronary intervention: design and rationale of the randomised FAVOR III Europe Japan trial.
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Andersen, Birgitte Krogsgaard (author)
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Sejr-Hansen, Martin (author)
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Westra, Jelmer (author)
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Campo, Gianluca (author)
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Efterkhari, Ashkan (author)
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Tu, Shengxian (author)
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Escaned, Javier (author)
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Koltowski, Lukasz (author)
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Stähli, Barbara E (author)
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Erglis, Andrejs (author)
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Jaruševičius, Gediminas (author)
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Žiubrytė, Greta (author)
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- Råmunddal, Truls, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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Liu, Tommy (author)
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Wijns, William (author)
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Landmesser, Ulf (author)
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Maillard, Luc (author)
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Matsuo, Hitoshi (author)
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Christiansen, Evald Høj (author)
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Holm, Niels Ramsing (author)
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- 2023
- 2023
- English.
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In: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. - 1969-6213.
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https://doi.org/10.4...
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Abstract
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- Quantitative flow ratio (QFR) is a computation of fractional flow reserve (FFR) based on invasive coronary angiographic images. Calculating QFR is less invasive than measuring FFR and may be associated with lower costs. Current evidence supports the call for an adequately powered randomised comparison of QFR and FFR for the evaluation of intermediate coronary stenosis. The aim of the FAVOR III Europe Japan trial is to investigate if a QFR-based diagnostic strategy yields a non-inferior 12-month clinical outcome compared with a standard FFR-guided strategy in the evaluation of patients with intermediary coronary stenosis. FAVOR III Europe Japan is an investigator-initiated, randomised, clinical outcome, non-inferiority trial scheduled to randomise 2,000 patients with either 1) stable angina pectoris and intermediate coronary stenosis, or 2) indications for functional assessment of at least 1 non-culprit lesion after acute myocardial infarction. Up to 40 international centres will randomise patients to either a QFR-based or a standard FFR-based diagnostic strategy. The primary endpoint of major adverse cardiovascular events is a composite of all-cause mortality, any myocardial infarction, and any unplanned coronary revascularisation at 12 months. QFR could emerge as an adenosine- and wire-free alternative to FFR, making the functional evaluation of intermediary coronary stenosis less invasive and more cost-effective.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Andersen, Birgit ...
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Sejr-Hansen, Mar ...
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Westra, Jelmer
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Campo, Gianluca
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Efterkhari, Ashk ...
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Tu, Shengxian
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show more...
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Escaned, Javier
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Koltowski, Lukas ...
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Stähli, Barbara ...
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Erglis, Andrejs
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Jaruševičius, Ge ...
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Žiubrytė, Greta
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Råmunddal, Truls ...
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Liu, Tommy
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Wijns, William
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Landmesser, Ulf
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Maillard, Luc
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Matsuo, Hitoshi
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Christiansen, Ev ...
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Holm, Niels Rams ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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EuroIntervention ...
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University of Gothenburg