SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:gup.ub.gu.se/326367"
 

Search: onr:"swepub:oai:gup.ub.gu.se/326367" > Transcatheter Mitra...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004983naa a2200829 4500
001oai:gup.ub.gu.se/326367
003SwePub
008240528s2023 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3263672 URI
0247 a https://doi.org/10.1161/CIRCINTERVENTIONS.123.0130452 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Ludwig, Sebastian4 aut
2451 0a Transcatheter Mitral Valve Replacement versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score-Matched Comparison.
264 1c 2023
520 a Background: Transcatheter mitral valve replacement (TMVR) is an emerging therapeutic alternative for patients with secondary mitral regurgitation (MR). Outcomes of TMVR versus guideline-directed medical therapy (GDMT) have not been investigated for this population. This study aimed to compare clinical outcomes of patients with secondary MR undergoing TMVR versus GDMT alone. Methods: The CHOICE-MI registry included patients with MR undergoing TMVR using dedicated devices. Patients with MR etiologies other than secondary MR were excluded. Patients treated with GDMT alone were derived from the control arm of the COAPT trial. We compared outcomes between the TMVR and GDMT groups, using propensity score (PS)-matching to adjust for baseline differences. Results: After PS-matching, 97 patient pairs undergoing TMVR (72.9±8.7 years, 60.8% male, transapical access 91.8%) versus GDMT (73.1±11.0 years, 59.8% male) were compared. At 1 and 2 years, residual MR was ≤1+ in all patients of the TMVR group compared to 6.9% and 7.7%, respectively, in those receiving GDMT alone (both p<0.001). The 2-year rate of HF hospitalization was significantly lower in the TMVR group (32.8% vs. 54.4%, HR 0.59, 95% CI 0.35-0.99; p=0.04). Among survivors, a higher proportion of patients were in NYHA functional class I or II in the TMVR group at 1 year (78.2% vs. 59.7%, p=0.03) and at 2 years (77.8% vs. 53.2%, p=0.09). Two-year mortality was similar in the two groups (TMVR vs. GDMT, 36.8% vs. 40.8%, HR 1.01, 95% CI 0.62-1.64; p=0.98). Conclusions: In this observational comparison, over 2-year follow-up, TMVR using mostly transapical devices in patients with secondary MR was associated with significant reduction of MR, symptomatic improvement, less frequent hospitalizations for HF and similar mortality compared with GDMT.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
7001 a Conradi, Lenard4 aut
7001 a Cohen, David J4 aut
7001 a Coisne, Augustin4 aut
7001 a Scotti, Andrea4 aut
7001 a Abraham, William T4 aut
7001 a Ben Ali, Walid4 aut
7001 a Zhou, Zhipeng4 aut
7001 a Li, Yanru4 aut
7001 a Kar, Saibal4 aut
7001 a Duncan, Alison4 aut
7001 a Lim, D Scott4 aut
7001 a Adamo, Marianna4 aut
7001 a Redfors, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xredbj
7001 a Muller, David W M4 aut
7001 a Webb, John G4 aut
7001 a Petronio, Anna Sonia4 aut
7001 a Ruge, Hendrik4 aut
7001 a Nickenig, Georg4 aut
7001 a Sondergaard, Lars4 aut
7001 a Adam, Matti4 aut
7001 a Regazzoli, Damiano4 aut
7001 a Garatti, Andrea4 aut
7001 a Schmidt, Tobias4 aut
7001 a Andreas, Martin4 aut
7001 a Dahle, Gry4 aut
7001 a Walther, Thomas4 aut
7001 a Kempfert, Joerg4 aut
7001 a Tang, Gilbert Hl4 aut
7001 a Redwood, Simon R4 aut
7001 a Taramasso, Maurizio4 aut
7001 a Praz, Fabien4 aut
7001 a Fam, Neil P4 aut
7001 a Dumonteil, Nicolas4 aut
7001 a Obadia, Jean-François4 aut
7001 a von Bardeleben, Ralph Stephan4 aut
7001 a Rudolph, Tanja Katharina4 aut
7001 a Reardon, Michael J4 aut
7001 a Metra, Marco4 aut
7001 a Denti, Paolo4 aut
7001 a Mack, Michael J4 aut
7001 a Hausleiter, Jörg4 aut
7001 a Asch, Federico M4 aut
7001 a Latib, Azeem4 aut
7001 a Lindenfeld, JoAnn4 aut
7001 a Modine, Thomas4 aut
7001 a Stone, Gregg W4 aut
7001 a Granada, Juan F4 aut
7102 a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
7730 t Circulation. Cardiovascular interventionsg 16:6q 16:6x 1941-7632
8564 8u https://gup.ub.gu.se/publication/326367
8564 8u https://doi.org/10.1161/CIRCINTERVENTIONS.123.013045

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view