Facial pain, health-related quality of life and trismus-related symptoms up to 5years post-radiotherapy for head and neck cancer

Aghajanzadeh, SusanGothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology (author)

Purpose: Pain is a frequent symptom of head and neck cancer (HNC) but longitudinal studies investigating facial pain are scarce. We aimed to investigate prevalence of facial pain, its effect on health-related quality of life (HRQL) and trismus-related symptoms in a HNC cohort. Methods: Patients (n = 194) were prospectively followed post completion of radiotherapy (RT). Outcome measures included facial pain, HRQL, trismus-specific symptoms, and maximal interincisal opening (MIO). Results: Facial pain was reported by 50% at baseline. Corresponding figures for 3-, 12-, and 60months post-RT were 70%, 54% and 41%. Moderate to severe pain was reported in 29–44% of patients reporting pain during the study period. Patients reporting pain scored significantly worse on more HRQL variables and trismus symptoms, as well as had significantly smaller MIO at all follow-up time points. Conclusions: Facial pain was common in HNC patients pre- and post-RT and remained prevalent up to 5years after completion of RT. Reductions in MIO were associated with more facial pain. Pain was also associated with worse HRQL.

Karlsson, Therese,1987Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xkther (author)
Tuomi, Lisa,1985Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Neuroscience and Physiology,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xtuoli (author)
Engström, My,1977Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences(Swepub:gu)xsvemy (author)
Finizia, Caterina,1961Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xfinca (author)
Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar (creator_code:org_t)

By the author/editor: Aghajanzadeh, Su ...; Karlsson, Theres ...; Tuomi, Lisa, 198 ...; Engström, My, 19 ...; Finizia, Caterin ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Otorhinolaryngol ...

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