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Prognostic value of a composite outcome measure for periodontal stability following periodontal regenerative treatment: A retrospective analysis at 4 years

Simonelli, A. (author)
Farina, R. (author)
Minenna, L. (author)
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Tomasi, Cristiano, 1964 (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2
Trombelli, L. (author)
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 (creator_code:org_t)
2023
2023
English.
In: Journal of Periodontology. - 0022-3492. ; 94:9, s. 1090-1099
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • BackgroundRecently, a composite outcome measure (COM) was proposed to describe the short-term results of periodontal regenerative treatment. The present retrospective study aimed at evaluating the prognostic value of COM on clinical attachment level (CAL) change over a 4-year period of supportive periodontal care (SPC). MethodsSeventy-four intraosseous defects in 59 patients were evaluated at 6 months and 4 years following regenerative treatment. Based on 6-month CAL change and probing depth (PD), defects were classified as: COM1 (CAL gain & GE;3 mm, PD & LE;4 mm); COM2 (CAL gain <3 mm, PD & LE;4 mm); COM3 (CAL gain & GE;3 mm, PD >4 mm); or COM4 (CAL gain <3 mm, PD >4 mm). COM groups were compared for "stability" (i.e., CAL gain, no change in CAL or CAL loss <1 mm) at 4 years. Also, groups were compared for mean change in PD and CAL, need for surgical retreatment, and tooth survival. ResultsAt 4 years, the proportion of stable defects in COM1, COM2, COM3, and COM4 group was 69.2%, 75%, 50%, and 28.6%, respectively, with a substantially higher probability for a defect to show stability for COM1, COM2, and COM3 compared with COM4 (odds ratio 4.6, 9.1, and 2.4, respectively). Although higher prevalence of surgical reinterventions and lower tooth survival were observed in COM4, no significant differences were detected among COM groups. ConclusionsCOM may be of value in predicting CAL change at sites undergoing SPC following periodontal regenerative surgery. Studies on larger cohorts, however, are needed to substantiate the present findings.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Keyword

periodontal attachment loss
periodontal diseases
periodontitis
prognosis
reconstructive surgical procedures
regeneration
supportive
periodontal therapy
treatment outcome
single-flap-approach
guided tissue regeneration
enamel matrix
proteins
intra-bony defects
intraosseous defects
residual pockets
tooth loss
long-term
access
progression
Dentistry
Oral Surgery & Medicine

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ref (subject category)
art (subject category)

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By the author/editor
Simonelli, A.
Farina, R.
Minenna, L.
Tomasi, Cristian ...
Trombelli, L.
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Dentistry
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Journal of Perio ...
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University of Gothenburg

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