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Single Troponin Mea...
Single Troponin Measurement to Rule Out Myocardial Infarction: JACC Review Topic of the Week
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Jaffe, Allan S. (author)
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Body, Richard (author)
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Mills, Nicholas L. (author)
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Aakre, Kristin M. (author)
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Collinson, Paul O. (author)
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Saenger, Amy (author)
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- Hammarsten, Ola (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för laboratoriemedicin,Department of Laboratory Medicine
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Wereski, Ryan (author)
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Omland, Torbjørn (author)
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Sandoval, Yader (author)
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Ordonez-Llanos, Jordi (author)
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Apple, Fred S. (author)
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(creator_code:org_t)
- 2023
- 2023
- English.
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In: Journal of the American College of Cardiology. - 0735-1097 .- 1558-3597. ; 82:1, s. 60-69
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Abstract
Subject headings
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- The term “single-sample rule-out” refers to the ability of very low concentrations of high-sensitivity cardiac troponin (hs-cTn) on presentation to exclude acute myocardial infarction with high clinical sensitivity and negative predictive value. Observational and randomized studies have confirmed this ability. Some guidelines endorse use of a concentration of hs-cTn at the assay's limit of detection, while other studies have validated the use of higher concentrations, allowing this approach to identify a greater proportion of patients at low risk. In most studies, at least 30% of patients can be triaged with this approach. The concentration of hs-cTn varies according to the assay used and sometimes how regulations permit reporting. It is clear that patients need to be at least 2 hours from the onset of symptoms being evaluated. Caution is warranted, particularly with older patients, women, and patients with underlying cardiac comorbidities.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- infarction
- myocardial infarction
- troponin
Publication and Content Type
- ref (subject category)
- for (subject category)
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- By the author/editor
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Jaffe, Allan S.
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Body, Richard
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Mills, Nicholas ...
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Aakre, Kristin M ...
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Collinson, Paul ...
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Saenger, Amy
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show more...
-
Hammarsten, Ola
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Wereski, Ryan
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Omland, Torbjørn
-
Sandoval, Yader
-
Ordonez-Llanos, ...
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Apple, Fred S.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Journal of the A ...
- By the university
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University of Gothenburg