Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories

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Fältnamn	Indikatorer	Metadata
000		08936naa a2201957 4500
001		oai:gup.ub.gu.se/336397
003		SwePub
008		240528s2024 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:155340775
024	7	a https://gup.ub.gu.se/publication/3363972 URI
024	7	a https://doi.org/10.1016/j.jhep.2023.10.0432 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1553407752 URI
040		a (SwePub)gud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Razavi-Shearer, Devin M.4 aut
245	1 0	a Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories
264	1	c 2024
520		a Background & Aims: Hepatitis delta virus (HDV) is a satellite RNA virus that requires the hepatitis B virus (HBV) for assembly and propagation. Individuals infected with HDV progress to advanced liver disease faster than HBV-monoinfected individuals. Recent studies have estimated the global prevalence of anti-HDV antibodies among the HBV-infected population to be 5-15%. This study aimed to better understand HDV prevalence at the population level in 25 countries/territories. Methods: We conducted a literature review to determine the prevalence of anti-HDV and HDV RNA in hepatitis B surface antigen (HBsAg)-positive individuals in 25 countries/territories. Virtual meetings were held with experts from each setting to discuss the findings and collect unpublished data. Data were weighted for patient segments and regional heterogeneity to estimate the prevalence in the HBV-infected population. The findings were then combined with The Polaris Observatory HBV data to estimate the anti-HDV and HDV RNA prevalence in each country/territory at the population level. Results: After adjusting for geographical distribution, disease stage and special populations, the anti-HDV prevalence among the HBsAg+ population changed from the literature estimate in 19 countries. The highest anti-HDV prevalence was 60.1% in Mongolia. Once adjusted for the size of the HBsAg+ population and HDV RNA positivity rate, China had the highest absolute number of HDV RNA+ cases. Conclusions: We found substantially lower HDV prevalence than previously reported, as prior meta-analyses primarily focused on studies conducted in groups/regions that have a higher probability of HBV infection: tertiary care centers, specific risk groups or geographical regions. There is large uncertainty in HDV prevalence estimates. The implementation of reflex testing would improve estimates, while also allowing earlier linkage to care for HDV RNA+ individuals. The logistical and economic burden of reflex testing on the health system would be limited, as only HBsAg+ cases would be screened.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
700	1	a Buti, Maria4 aut
700	1	a Tacke, Frank4 aut
700	1	a Terrault, Norah A.4 aut
700	1	a Zeuzem, Stefan4 aut
700	1	a Abbas, Zaigham4 aut
700	1	a Aghemo, Alessio4 aut
700	1	a Akarca, Ulus S.4 aut
700	1	a Al Masri, Nasser M.4 aut
700	1	a Alalwan, Abduljaleel M.4 aut
700	1	a Blome, Marianne Alanko4 aut
700	1	a Aleman, Soou Karolinska Institutet4 aut
700	1	a Alghamdi, Abdullah S.4 aut
700	1	a Alghamdi, Mohammed4 aut
700	1	a Alghamdi, Saad4 aut
700	1	a Al-Hamoudi, Waleed K.4 aut
700	1	a Ali, Ela4 aut
700	1	a Aljumah, Abdulrahman A.4 aut
700	1	a Altraif, Ibrahim H.4 aut
700	1	a Amarsanaa, Jazag4 aut
700	1	a Asselah, Tarik4 aut
700	1	a Baatarkhuu, Oidov4 aut
700	1	a Babameto, Adriana4 aut
700	1	a Ben-Ari, Ziv4 aut
700	1	a Berg, Thomas4 aut
700	1	a Biondi, Mia J.4 aut
700	1	a Braga, Wornei S. M.4 aut
700	1	a Brandao-Mello, Carlos E.4 aut
700	1	a Jr, Robert S. Brown4 aut
700	1	a Brunetto, Maurizia R.4 aut
700	1	a Cabezas, Joaquin4 aut
700	1	a Cardoso, Mariana4 aut
700	1	a Chan, Henry Lik Yuen4 aut
700	1	a Cheinquer, Hugo4 aut
700	1	a Chen, Chien-Jen4 aut
700	1	a Chen, Pei-Jer4 aut
700	1	a Chien, Cheng-Hung4 aut
700	1	a Child, Hailey4 aut
700	1	a Chuang, Wan-Long4 aut
700	1	a Garza, Laura E. Cisneros4 aut
700	1	a Coco, Barbara4 aut
700	1	a Coffin, Carla S.4 aut
700	1	a Coppola, Nicola4 aut
700	1	a Cornberg, Markus4 aut
700	1	a Craxi, Antonio4 aut
700	1	a Crespo, Javier4 aut
700	1	a Cuko, Liri4 aut
700	1	a De Ledinghen, Victor4 aut
700	1	a Duberg, Ann-Sofi4 aut
700	1	a Etzion, Ohad4 aut
700	1	a Ferraz, Maria Lucia G.4 aut
700	1	a Ferreira, Paulo R. A.4 aut
700	1	a Forns, Xavier4 aut
700	1	a Foster, Graham R.4 aut
700	1	a Fung, James4 aut
700	1	a Gaeta, Giovanni B.4 aut
700	1	a Garcia-Samaniego, Javier4 aut
700	1	a Genov, Jordan4 aut
700	1	a Gheorghe, Liliana S.4 aut
700	1	a Gholam, Pierre M.4 aut
700	1	a Gish, Robert G.4 aut
700	1	a Glenn, Jeffrey4 aut
700	1	a Goldis, Adrian4 aut
700	1	a Hamid, Saeed S.4 aut
700	1	a Hercun, Julian4 aut
700	1	a Hsu, Yao-Chun4 aut
700	1	a Hu, Ching-Chih4 aut
700	1	a Huang, Jee-Fu4 aut
700	1	a Idilman, Ramazan4 aut
700	1	a Jafri, Wasim S. M.4 aut
700	1	a Janjua, Naveed4 aut
700	1	a Jelev, Deian4 aut
700	1	a Jerkeman, Anna4 aut
700	1	a Jia, Jidong4 aut
700	1	a Kaberg, Martin4 aut
700	1	a Kaita, Kelly D. E.4 aut
700	1	a Kao, Jia-Horng4 aut
700	1	a Khan, Aamir G.4 aut
700	1	a Kim, Do Young4 aut
700	1	a Kondili, Loreta A.4 aut
700	1	a Lagging, Martin,d 1965u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xlagma
700	1	a Lampertico, Pietro4 aut
700	1	a Lazaro, Pablo4 aut
700	1	a Lazarus, Jeffrey4 aut
700	1	a Lee, Mei-Hsuan4 aut
700	1	a Lim, Young-Suk4 aut
700	1	a Lobato, Cirley M. O.4 aut
700	1	a Macedo, Guilherme4 aut
700	1	a Marinho, Rui T.4 aut
700	1	a Marotta, Paul J.4 aut
700	1	a Martins, Alexanda4 aut
700	1	a Mendes-Correa, Maria Cassia4 aut
700	1	a Mendez-Sanchez, Nahum4 aut
700	1	a Navas, Maria-Cristina4 aut
700	1	a Ning, Qing4 aut
700	1	a Ormeci, Necati4 aut
700	1	a Orrego, Mauricio4 aut
700	1	a Osiowy, Carla4 aut
700	1	a Pan, Calvin Q.4 aut
700	1	a Pessoa, Mario G.4 aut
700	1	a Piracha, Zahra Z.4 aut
700	1	a Pop, Cora4 aut
700	1	a Ramos, Jose A. Presa4 aut
700	1	a Qureshi, Huma4 aut
700	1	a Raimondo, Giovanni4 aut
700	1	a Ramji, Alnoor4 aut
700	1	a Razavi-Shearer, Kathryn4 aut
700	1	a Ribeiro, Sofia4 aut
700	1	a Rios-Hincapie, Cielo Y.4 aut
700	1	a Rodriguez, Manuel4 aut
700	1	a Rosenberg, William M. C.4 aut
700	1	a Roulot, Dominique4 aut
700	1	a Ryder, Stephen D.4 aut
700	1	a Saeed, Umar4 aut
700	1	a Safadi, Rifaat4 aut
700	1	a Sanai, Faisal M.4 aut
700	1	a Sanchez-Avila, Juan F.4 aut
700	1	a Santantonio, Teresa A.4 aut
700	1	a Sarrazin, Christoph4 aut
700	1	a Seto, Wai-Kay4 aut
700	1	a Shouval, Daniel4 aut
700	1	a Simonova, Marieta Y.4 aut
700	1	a Tanaka, Junko4 aut
700	1	a Tergast, Tammo L.4 aut
700	1	a Tsendsuren, Oyunsuren4 aut
700	1	a Valente, Cristina4 aut
700	1	a Villalobos-Salcedo, Juan Miguel4 aut
700	1	a Voeller, Alexis S.4 aut
700	1	a Waheed, Yasir4 aut
700	1	a Wong, Grace L-H4 aut
700	1	a Wong, Vincent W-S4 aut
700	1	a Wu, Jaw-Ching4 aut
700	1	a Yang, Hwai-4 aut
700	1	a Yip, Terry C-F4 aut
700	1	a Yu, Ming-Lung4 aut
700	1	a Yuen, Man-Fung4 aut
700	1	a Yurdaydin, Cihan4 aut
700	1	a Zuckerman, Eli4 aut
700	1	a Razavi, Homie A.4 aut
710	2	a Karolinska Institutetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org
773	0	t JOURNAL OF HEPATOLOGYg 80:2, s. 232-242q 80:2<232-242x 0168-8278x 1600-0641
856	4 8	u https://gup.ub.gu.se/publication/336397
856	4 8	u https://doi.org/10.1016/j.jhep.2023.10.043
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:155340775

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By the author/editor: Razavi-Shearer, ...; Buti, Maria; Tacke, Frank; Terrault, Norah ...; Zeuzem, Stefan; Abbas, Zaigham; show more...; Aghemo, Alessio; Akarca, Ulus S.; Al Masri, Nasser ...; Alalwan, Abdulja ...; Blome, Marianne ...; Aleman, Soo; Alghamdi, Abdull ...; Alghamdi, Mohamm ...; Alghamdi, Saad; Al-Hamoudi, Wale ...; Ali, Ela; Aljumah, Abdulra ...; Altraif, Ibrahim ...; Amarsanaa, Jazag; Asselah, Tarik; Baatarkhuu, Oido ...; Babameto, Adrian ...; Ben-Ari, Ziv; Berg, Thomas; Biondi, Mia J.; Braga, Wornei S. ...; Brandao-Mello, C ...; Jr, Robert S. Br ...; Brunetto, Mauriz ...; Cabezas, Joaquin; Cardoso, Mariana; Chan, Henry Lik ...; Cheinquer, Hugo; Chen, Chien-Jen; Chen, Pei-Jer; Chien, Cheng-Hun ...; Child, Hailey; Chuang, Wan-Long; Garza, Laura E. ...; Coco, Barbara; Coffin, Carla S.; Coppola, Nicola; Cornberg, Markus; Craxi, Antonio; Crespo, Javier; Cuko, Liri; De Ledinghen, Vi ...; Duberg, Ann-Sofi; Etzion, Ohad; Ferraz, Maria Lu ...; Ferreira, Paulo ...; Forns, Xavier; Foster, Graham R ...; Fung, James; Gaeta, Giovanni ...; Garcia-Samaniego ...; Genov, Jordan; Gheorghe, Lilian ...; Gholam, Pierre M ...; Gish, Robert G.; Glenn, Jeffrey; Goldis, Adrian; Hamid, Saeed S.; Hercun, Julian; Hsu, Yao-Chun; Hu, Ching-Chih; Huang, Jee-Fu; Idilman, Ramazan; Jafri, Wasim S. ...; Janjua, Naveed; Jelev, Deian; Jerkeman, Anna; Jia, Jidong; Kaberg, Martin; Kaita, Kelly D. ...; Kao, Jia-Horng; Khan, Aamir G.; Kim, Do Young; Kondili, Loreta ...; Lagging, Martin, ...; Lampertico, Piet ...; Lazaro, Pablo; Lazarus, Jeffrey; Lee, Mei-Hsuan; Lim, Young-Suk; Lobato, Cirley M ...; Macedo, Guilherm ...; Marinho, Rui T.; Marotta, Paul J.; Martins, Alexand ...; Mendes-Correa, M ...; Mendez-Sanchez, ...; Navas, Maria-Cri ...; Ning, Qing; Ormeci, Necati; Orrego, Mauricio; Osiowy, Carla; Pan, Calvin Q.; Pessoa, Mario G.; Piracha, Zahra Z ...; Pop, Cora; Ramos, Jose A. P ...; Qureshi, Huma; Raimondo, Giovan ...; Ramji, Alnoor; Razavi-Shearer, ...; Ribeiro, Sofia; Rios-Hincapie, C ...; Rodriguez, Manue ...; Rosenberg, Willi ...; Roulot, Dominiqu ...; Ryder, Stephen D ...; Saeed, Umar; Safadi, Rifaat; Sanai, Faisal M.; Sanchez-Avila, J ...; Santantonio, Ter ...; Sarrazin, Christ ...; Seto, Wai-Kay; Shouval, Daniel; Simonova, Mariet ...; Tanaka, Junko; Tergast, Tammo L ...; Tsendsuren, Oyun ...; Valente, Cristin ...; Villalobos-Salce ...; Voeller, Alexis ...; Waheed, Yasir; Wong, Grace L-H; Wong, Vincent W- ...; Wu, Jaw-Ching; Yang, Hwai-; Yip, Terry C-F; Yu, Ming-Lung; Yuen, Man-Fung; Yurdaydin, Cihan; Zuckerman, Eli; Razavi, Homie A.; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Gastroenterology ...

Articles in the publication: JOURNAL OF HEPAT ...

By the university: University of Gothenburg; Karolinska Institutet

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