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Occupational partic...
Occupational particle exposure and chronic kidney disease: a cohort study in Swedish construction workers.
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- Kilbo Edlund, Karl (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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- Andersson, Eva M., 1968 (author)
- Umeå universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden,Institutionen för folkhälsa och klinisk medicin
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Andersson, Martin (author)
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- Barregård, Lars, 1948 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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- Christensson, Anders (author)
- Department of Nephrology, Lund University, Lund, Sweden; Department of Nephrology, Skåne University Hospital Nephrology, Malmö, Sweden
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- Johannesson, Sandra, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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- Harari, Florencia, 1986 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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- Murgia, Nicola (author)
- Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy
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- Torén, Kjell, 1952 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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- Stockfelt, Leo, 1981 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, University of Gothenburg, Göteborg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
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(creator_code:org_t)
- BMJ Publishing Group Ltd, 2024
- 2024
- English.
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In: Journal of Occupational and Environmental Medicine. - : BMJ Publishing Group Ltd. - 1351-0711 .- 1470-7926. ; 81:5, s. 238-243
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Abstract
Subject headings
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- Increasing epidemiological and experimental evidence suggests that particle exposure is an environmental risk factor for chronic kidney disease (CKD). However, only a few case-control studies have investigated this association in an occupational setting. Hence, our objective was to investigate associations between particle exposure and CKD in a large cohort of Swedish construction workers.We performed a retrospective cohort study in the Swedish Construction Workers' Cohort, recruited 1971-1993 (n=286089). A job-exposure matrix was used to identify workers exposed to nine different particulate exposures, which were combined into three main categories (inorganic dust and fumes, wood dust and fibres). Incident CKD and start of renal replacement therapy (RRT) were obtained from validated national registries until 2021 and analysed using adjusted Cox proportional hazards models.Exposure to inorganic dust and fumes was associated with an increased risk of CKD and RRT during working age (adjusted HR for CKD at age <65 years 1.15, 95%CI 1.05 to 1.26). The elevated risk did not persist after retirement age. Exposure to cement dust, concrete dust and diesel exhaust was associated with CKD. Elevated HRs were also found for quartz dust and welding fumes.Workers exposed to inorganic particles seem to be at elevated risk of CKD and RRT. Our results are in line with previous evidence of renal effects of ambient air pollution and warrant further efforts to reduce occupational and ambient particle exposure.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- Humans
- Occupational Exposure
- adverse effects
- Sweden
- epidemiology
- Renal Insufficiency
- Chronic
- epidemiology
- etiology
- Middle Aged
- Male
- Dust
- Adult
- Construction Industry
- statistics & numerical data
- Retrospective Studies
- Occupational Diseases
- epidemiology
- etiology
- Particulate Matter
- adverse effects
- analysis
- Female
- Aged
- Risk Factors
- Air Pollutants
- Occupational
- adverse effects
- Proportional Hazards Models
- Cohort Studies
- Vehicle Emissions
- analysis
- Construction Materials
- adverse effects
- Wood
- Dust
Publication and Content Type
- ref (subject category)
- art (subject category)
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Kilbo Edlund, Ka ...
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Andersson, Eva M ...
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Andersson, Marti ...
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Barregård, Lars, ...
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Christensson, An ...
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Johannesson, San ...
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Harari, Florenci ...
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Murgia, Nicola
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Torén, Kjell, 19 ...
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Stockfelt, Leo, ...
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University of Gothenburg
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Umeå University