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  • Bülow, Birgitta (author)

Adrenal incidentaloma - follow-up results from a Swedish prospective study

  • Article/chapterEnglish2006

Publisher, publication year, extent ...

  • Oxford University Press (OUP),2006

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/48383
  • https://gup.ub.gu.se/publication/48383URI
  • https://doi.org/10.1530/eje.1.02110DOI
  • https://lup.lub.lu.se/record/410847URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:1946906URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-37623URI

Supplementary language notes

  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • OBJECTIVES: To examine the risk of developing adrenal carcinomas and clinically overt hypersecreting tumours during short-term follow-up in patients with adrenal incidentalomas. DESIGN: 229 (98 males and 131 females) patients with adrenal incidentalomas were investigated in a prospective follow-up study (median time 25 months; range 3-108 months). The patients were registered between January 1996 and July 2001 and followed until December 2004. Twenty-seven Swedish hospitals contributed with follow-up results. METHODS: Diagnostic procedures were undertaken according to a protocol including reinvestigation with computed tomography scans after 3-6 months, 15-18 months and 27-30 months, as well as hormonal evaluation at baseline and after 27-30 months of follow-up. Operation was recommended when the incidentaloma size increased or if there was a suspicion of a hypersecreting tumour. RESULTS: The median age at diagnosis of the 229 patients included in the follow-up study was 64 years (range 28-84 years) and the median size of the adrenal incidentalomas when discovered was 2.5 cm (range 1-8 cm). During the follow-up period, an increase in incidentaloma size of > or =0.5 cm was reported in 17 (7.4%) and of > or =1.0 cm was reported in 12 (5.2%) of the 229 patients. A decrease in size was seen in 12 patients (5.2%). A hypersecreting tumour was found in 2% of the hormonally investigated patients: Cushing's syndrome (n = 2) and phaeochromocytoma (n = 1). Eleven patients underwent adrenalectomy, but no cases of primary adrenal malignancy were observed. CONCLUSIONS: Patients with adrenal incidentaloma had a low risk of developing malignancy or hormonal hypersecretion during a short-term follow-up period.

Subject headings and genre

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  • Jansson, Svante,1948Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xjanss (author)
  • Juhlin, Claes,1952-Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Avdelningen för kirurgi,Kirurgiska kliniken i Östergötland med verksamhet i Linköping, Norrköping och Motala(Swepub:liu)claju74 (author)
  • Steen, Lars (author)
  • Thorén, MarjaKarolinska Institutet (author)
  • Wahrenberg, H. (author)
  • Valdemarsson, StigLund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-sva (author)
  • Wängberg, Bo,1953Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xwanbo (author)
  • Ahrén, BoLund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-bah (author)
  • Wahrenberg, L (author)
  • Göteborgs universitetInstitutionen för kliniska vetenskaper (creator_code:org_t)

Related titles

  • In:European journal of endocrinology / European Federation of Endocrine Societies: Oxford University Press (OUP)154:3, s. 419-230804-46431479-683X
  • In:European Journal of Endocrinology: Oxford University Press (OUP)154:3, s. 419-231479-683X

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