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The E/e filling ind...
The E/e filling index and right ventricular pressure in relation to applied international Doppler recommendations of left ventricular filling assessment
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Guron, Cecilia Wallentin, 1965 (author)
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- Bech-Hanssen, Odd, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för fysiologi,Institute of Physiology and Pharmacology, Dept of Physiology
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Wikh, R. (author)
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- Rosengren, Annika, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin,Institute of Internal Medicine
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- Hartford, Marianne, 1944 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Caidahl, Kenneth, 1949 (author)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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(creator_code:org_t)
- Oxford University Press (OUP), 2005
- 2005
- English.
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In: Eur J Echocardiogr. - : Oxford University Press (OUP). - 1525-2167. ; 6:6, s. 419-28
- Related links:
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https://doi.org/10.1...
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Abstract
Subject headings
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- AIM: A ratio>15 between the early diastolic pulsed Doppler velocities of the mitral inflow (E) and the basal left ventricular (LV) tissue (e) has been demonstrated to predict an elevated LV filling pressure (FP). An elevated LVFP implies an elevated right ventricular pressure (RVp). In order to investigate the sensitivity of the E/e filling index, we compared E/e and RVp, in their ability to identify a Doppler-assumed elevation of LVFP. METHODS AND RESULTS: Application of pulsed Doppler international recommendations grouped 134 patients with acute coronary syndromes (ACS) and 50 age- and sex-matched controls, according to LV filling: normal; delayed relaxation; an isolated pathological mitral-pulmonary venous-A-wave-duration difference; pseudo normal; or a restrictive filling pattern. An E/e>15 and an RVp>30 mmHg showed the following (%) sensitivity (32/94), specificity (95/76), positive (68/59), and negative (80/97) predictive values of a Doppler-assumed elevation of LVFP, in terms of either a pseudo normal or a restrictive filling pattern. CONCLUSION: The low sensitivity of E/e to detect a Doppler-assumed elevation of LVFP could limit its clinical usefulness as a single variable, in ACS. The high sensitivity and negative predictive value of RVp support its use as an additional LV filling variable in these patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Aged
- Coronary Disease/physiopathology/ultrasonography
- *Echocardiography
- Doppler
- Pulsed
- Female
- Heart Ventricles/physiology/*ultrasonography
- Humans
- Male
- Middle Aged
- Mitral Valve/physiology/ultrasonography
- Predictive Value of Tests
- Reproducibility of Results
- Sensitivity and Specificity
- *Ventricular Function
- Left
- *Ventricular Function
- Right
- *Ventricular Pressure
Publication and Content Type
- ref (subject category)
- art (subject category)
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