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  • Anh, Dang Duc (author)

Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.

  • Article/chapterEnglish2007

Publisher, publication year, extent ...

  • Elsevier BV,2007

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/54018
  • https://gup.ub.gu.se/publication/54018URI
  • https://doi.org/10.1016/j.vaccine.2006.09.049DOI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Vietnam currently produces an orally administered, bivalent (O1 and O139) killed whole-cell vaccine and is the only country in the world with endemic cholera to use an oral cholera vaccine in public health practice. In order to allow international use, the vaccine had to be reformulated to meet World Health Organization (WHO) requirements. We performed a randomized, placebo controlled, safety and immunogenicity studies of this reformulated vaccine among Vietnamese adults. One hundred and forty-four subjects received the two-dose regimen and 143 had two blood samples obtained for analysis. We found that this reformulated oral killed whole-cell cholera vaccine was safe, well tolerated and highly immunogenic.

Subject headings and genre

  • Administration
  • Oral
  • Adolescent
  • Adult
  • Cholera
  • immunology
  • microbiology
  • prevention & control
  • Cholera Vaccines
  • administration & dosage
  • adverse effects
  • immunology
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Vaccines
  • Inactivated
  • administration & dosage
  • adverse effects
  • immunology
  • Vibrio cholerae O1
  • immunology
  • Vibrio cholerae O139
  • immunology
  • Vietnam

Added entries (persons, corporate bodies, meetings, titles ...)

  • Canh, Do Gia (author)
  • Lopez, Anna Lena (author)
  • Thiem, Vu Dinh (author)
  • Long, Phan Thi (author)
  • Son, Nguyen Hong (author)
  • Deen, Jacqueline (author)
  • von Seidlein, Lorenz (author)
  • Carbis, Rodney (author)
  • Han, Seung Hyun (author)
  • Shin, Seong Hye (author)
  • Attridge, Stephen,1951Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi,Institute of Biomedicine, Department of Microbiology and Immunology(Swepub:gu)xattrs (author)
  • Holmgren, Jan,1944Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi,Institute of Biomedicine, Department of Microbiology and Immunology(Swepub:gu)xholja (author)
  • Clemens, John (author)
  • Göteborgs universitetInstitutionen för biomedicin, avdelningen för mikrobiologi och immunologi (creator_code:org_t)

Related titles

  • In:Vaccine: Elsevier BV25:6, s. 1149-550264-410X

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