Advances since the paper by Zander and Glass (1949) on the pursuit of healing methods for pulpal exposures: historical perspectives.

• Clinical observations and experimental studies in humans and laboratory animals have demonstrated that healing and repair of pulpal exposures by caries, trauma, or iatrogenic causes are possible with a variety of wound treatment methods. Yet clinical trials have shown that predictable long-term pulp tissue preservation may be an elusive goal and has led to doubts about pulp capping and pulpotomy as valid clinical procedures. Nevertheless substantial knowledge has accumulated over the years on the mechanisms and the treatment factors that are important to promote/support continued vital pulp functions. This article highlights some key contributions to our current knowledge base, which have come to light during the more than 50 years since a pioneering experimental study by Zander and Glass was published in the Triple O journal.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Keyword

Aluminum Compounds

therapeutic use

Animals

Calcium Compounds

therapeutic use

Calcium Hydroxide

therapeutic use

Dental Pulp Capping

history

methods

Dental Pulp Exposure

therapy

Dentin

Secondary

physiology

Drug Combinations

Growth Substances

pharmacology

History

20th Century

History

21st Century

Humans

Necrosis

physiopathology

Oxides

therapeutic use

Regeneration

drug effects

Root Canal Filling Materials

therapeutic use

Silicates

therapeutic use

Wound Healing

physiology

Publication and Content Type

ref (subject category)

for (subject category)