onr:"swepub:oai:gup.ub.gu.se/55545"
Search: onr:"swepub:oai:gup.ub.gu.se/55545" > Effects of the andr...
- 1 of 1
- Previous record
- Next record
- To hitlist
Effects of the androgen antagonist flutamide and the serotonin reuptake inhibitor citalopram in bulimia nervosa: a placebo-controlled pilot study.
-
- Sundblad-Elverfors, Charlotta, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology
- Landén, Mikael, 1966 (author)
-
- Eriksson, Tomas (author)
- Lund University,Lunds universitet,Forskningsgruppen för biologisk psykiatri,Forskargrupper vid Lunds universitet,The Biological Psychiatry Research Group,Lund University Research Groups
- show more...
- Bergman, Lars (author)
- show less...
- (creator_code:org_t)
- Ovid Technologies (Wolters Kluwer Health), 2005
- 2005
- English.
- In: Journal of clinical psychopharmacology. - : Ovid Technologies (Wolters Kluwer Health). - 0271-0749. ; 25:1, s. 85-8
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Prompted by previous studies suggesting that bulimia nervosa in women may be associated with elevated serum levels of testosterone, we have evaluated the possible effect of androgen antagonism in this condition. To this end, women meeting the DSM-IV criteria of bulimia nervosa, purging type, were treated in a one-center study with the androgen receptor antagonist flutamide (n = 9), the serotonin reuptake inhibitor citalopram (n = 15), flutamide plus citalopram (n = 10), or placebo (n = 12) for 3 months using a double-blind design. Self-rated global assessment of symptom intensity suggests all active treatments to be superior to placebo. The reduction in binge eating compared with baseline was statistically significant in both groups given flutamide but not in the groups given citalopram only or placebo. A moderate and reversible increase in serum transaminase levels led to discontinuation in two subjects in the flutamide group. It is concluded that blockade of androgen receptors may reduce some of the symptoms of bulimia nervosa in women.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- Adult
- Androgen Antagonists
- therapeutic use
- Bulimia
- drug therapy
- psychology
- Citalopram
- therapeutic use
- Double-Blind Method
- Drug Therapy
- Combination
- Female
- Flutamide
- therapeutic use
- Humans
- Male
- Middle Aged
- Pilot Projects
- Serotonin Uptake Inhibitors
- therapeutic use
- Transaminases
- blood
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Journal of clinical psychopharmacology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Sundblad-Elverfo ...
- Landén, Mikael, ...
- Eriksson, Tomas
- Bergman, Lars
- Eriksson, Elias, ...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Basic Medicine
- and Physiology
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Basic Medicine
- and Pharmacology and ...
- Articles in the publication
- Journal of clini ...
- By the university
- University of Gothenburg
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
