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Utility loss and indirect costs following cardiovascular events in hypertensive patients: the ASCOT health economic substudy

Lindgren, P. (author)
Kahan, T. (author)
Poulter, N. (author)
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Buxton, M. (author)
Svarvar, P. (author)
Dahlöf, Björn, 1953 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine
Jonsson, B. (author)
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 (creator_code:org_t)
2006
2006
English.
In: Eur J Health Econ. - 1618-7598.
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • This study assessed the loss of utility and indirect costs associated with first cardiovascular events. Data was collected (using EQ-5D) prospectively at 3, 6, and 12 months following an event in the Swedish part of the Anglo-Scandinavian cardiac outcomes trial (ASCOT), including patients with mild to moderate hypertension and additional risk factors. Sixty patients were eligible for analysis. An event was associated with a one-year utility loss of 0.075 (95% CI: 0.038-0.114). For a stroke, the reduction was 0.145 (CI: 0.059-0.249) and for acute coronary syndromes (myocardial infarction or unstable angina) the loss was 0.051 (-0.003 to 0.103). The utility at baseline was no different to the utility in a control group. The indirect cost over the first 12 months (2003 Swedish Kronor, SEK) was 90028 SEK (CI: 46027-146754), 9866 for patients in the workforce. These results are helpful in future economic evaluations of primary preventive measures in cardiovascular medicine.

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