Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms

Several studies have identified obesity as a risk factor for asthma in both children and adults. An increased prevalence of asthma in subjects with gastro-oesophageal reflux (GOR) and obstructive sleep apnoea syndrome has also been reported. The aim of this investigation was to study obesity, nocturnal GOR and snoring as independent risk factors for onset of asthma and respiratory symptoms in a Nordic population. In a 5-10 yr follow-up study of the European Community Respiratory Health Survey in Iceland, Norway, Denmark, Sweden and Estonia, a postal questionnaire was sent to previous respondents. A total of 16,191 participants responded to the questionnaire. Reported onset of asthma, wheeze and night-time symptoms as well as nocturnal GOR and habitual snoring increased in prevalence along with the increase in body mass index (BMI). After adjusting for nocturnal GOR, habitual snoring and other confounders, obesity (BMI >30) remained significantly related to the onset of asthma, wheeze and night-time symptoms. Nocturnal GOR was independently related to the onset of asthma and in addition, both nocturnal GOR and habitual snoring were independently related to onset of wheeze and night-time symptoms. This study adds evidence to an independent relationship between obesity, nocturnal gastro-oesophageal reflux and habitual snoring and the onset of asthma and respiratory symptoms in adults.

Omenaas, E. (author)
Gislason, T. (author)
Norrman, E. (author)
Olin, Anna-Carin,1960Gothenburg University,Göteborgs universitet,Institutionen för samhällsmedicin, Avdelningen för miljömedicin,Institute of Community Medicine, Dept of Primary Health Care(Swepub:gu)xolina (author)
Jogi, R. (author)
Jensen, E. J. (author)
Lindberg, E. (author)
Bjornsson, E. (author)
Franklin, K. (author)
Janson, C. (author)
Gulsvik, A. (author)
Laerum, B. (author)
Svanes, C. (author)
Torén, Kjell,1952Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin,Institutionen för samhällsmedicin, Avdelningen för miljömedicin,Institute of Internal Medicine,Institute of Community Medicine, Dept of Primary Health Care(Swepub:gu)xtorkj (author)
Tunsater, A. (author)
Lillienberg, Linnea,1942Gothenburg University,Göteborgs universitet,Institutionen för samhällsmedicin, Avdelningen för miljömedicin,Institute of Community Medicine, Dept of Primary Health Care(Swepub:gu)xlilli (author)
Gislason, D. (author)
Blondal, T. (author)
Bjornsdottir, U. S. (author)
Jorundsdottir, K. B. (author)
Talvik, R. (author)
Forsberg, B. (author)
Lundback, B. (author)
Soderberg, M. (author)
Ledin, M. C. (author)
Boman, G. (author)
Norback, D. (author)
Wieslander, G. (author)
Spetz-Nystrom, U. (author)
Cashelunge, K. S. (author)
Ryden, E. (author)
Göteborgs universitetInstitutionen för samhällsmedicin, Avdelningen för miljömedicin (creator_code:org_t)

In:Eur Respir J: European Respiratory Society (ERS)24:1
In:European Respiratory Journal: European Respiratory Society (ERS)24:10903-19361399-3003

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Respiratory Medi ...

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