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Evaluation of recon...
Evaluation of reconstruction techniques for lung single photon emission tomography: a Monte Carlo study.
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- Norberg, Pernilla, 1970- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet
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- Bake, Björn, 1939 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine,Sahlgrenska universitetssjukhuset, Göteborg
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- Jacobsson, Lars, 1947 (author)
- Göteborgs universitet, Göteborg
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- Alm Carlsson, Gudrun, 1939- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Hälsouniversitetet,Radiofysikavdelningen
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- Gustafsson, Agnetha (author)
- Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet
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(creator_code:org_t)
- United States : Lippincott Williams & Wilkins, 2007
- 2007
- English.
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In: Nuclear medicine communications. - United States : Lippincott Williams & Wilkins. - 0143-3636 .- 1473-5628. ; 28:12, s. 929-36
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- BACKGROUND: In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM: To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtered back-projection (FBP) for lung SPECT with Tc. METHODS: The evaluation of the number of iterations used in OSEM was based on the image quality parameter contrast. The comparison between OSEM and FBP was based on trade-off plots between statistical noise and spatial resolution for different filter parameters, collimators and count-levels. A Monte Carlo technique was used to simulate SPECT studies of a digital thorax phantom containing two sets of activity: one with a homogeneous activity distribution within the lungs and the other with superposed high- and low-activity objects. Statistical noise in the reconstructed images was calculated as the coefficient of variation (CV) and spatial resolution as full width at half-maximum (FWHM). RESULTS: For the configuration studied, the OSEM reconstruction in combination with post-filtering should be used in lung SPECT studies with at least 60 MLEM equivalent iterations. Compared to FBP the spatial resolution was improved by about 1 mm. For a constant level of CV, a four-fold increase in count level resulted in an increased resolution of about 2 mm. Spatial resolution and cut-off frequency depends on what value of noise in the image is acceptable also increased by using a low-energy, high-resolution collimator for CV values above 3%. The choice of noise-reducing filter and cut-off frequency depends on what value of noise in the image is acceptable.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- Algorithms
- Computer Simulation
- Humans
- Image Enhancement
- methods
- Image Interpretation
- Computer-Assisted
- methods
- Lung
- radionuclide imaging
- Models
- Biological
- Models
- Statistical
- Monte Carlo Method
- Reproducibility of Results
- Sensitivity and Specificity
- Tomography
- Emission-Computed
- Single-Photon
- methods
- SPECT
- MEDICINE
Publication and Content Type
- ref (subject category)
- art (subject category)
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