onr:"swepub:oai:gup.ub.gu.se/76311"
Search: onr:"swepub:oai:gup.ub.gu.se/76311" > Environmental salin...
- 1 of 1
- Previous record
- Next record
- To hitlist
Environmental salinity regulates receptor expression, cellular effects, and circulating levels of two antagonizing hormones, 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3, in rainbow trout.
- Larsson, D (author)
- Nemere, Ilka (author)
- Aksnes, Lage (author)
- show more...
- show less...
- (creator_code:org_t)
- 2003
- 2003
- English.
- In: Endocrinology. - 0013-7227. ; 144:2, s. 559-66
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- In freshwater-adapted rainbow trout, intestinal cells (enterocytes) possess receptors for 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] in the basolateral membrane, and respond to treatment with 1,25(OH)(2)D(3) with increased intracellular calcium concentrations. No receptors are found for the antagonizing hormone 24,25-dihydroxyvitamin D(3) [24,25(OH)(2)D(3)] at the enterocyte basolateral membrane, and it has no effect on enterocyte calcium homeostasis. After acclimation to seawater, however, the enterocyte membrane receptors for 1,25(OH)(2)D(3) are down-regulated and specific binding for 24,25(OH)(2)D(3) appears, which is further up-regulated with time spent in seawater. This shift in receptor expression is concurrent with an increased sensitivity of the enterocytes to 24,25(OH)(2)D(3) and a decreased sensitivity to 1,25(OH)(2)D(3). This results in a partial inhibition of intracellular calcium uptake, which would be beneficial when inhabiting a calcium-rich environment like seawater.
Subject headings
- NATURVETENSKAP -- Biologi -- Zoologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Zoology (hsv//eng)
Keyword
- 24
- 25-Dihydroxyvitamin D 3
- blood
- Adaptation
- Physiological
- physiology
- Animals
- Calcitriol
- blood
- Calcium
- metabolism
- Cell Membrane
- metabolism
- Enterocytes
- metabolism
- Environment
- Female
- Fresh Water
- Homeostasis
- physiology
- Male
- Oncorhynchus mykiss
- physiology
- Receptors
- Calcitriol
- metabolism
- Seawater
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Endocrinology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Larsson, D
- Nemere, Ilka
- Aksnes, Lage
- Sundell, Kristin ...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- and Zoology
- Articles in the publication
- Endocrinology
- By the university
- University of Gothenburg
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
