Search: onr:"swepub:oai:hhs.se:1155043100006056" >
Stochastic gene exp...
Stochastic gene expression in Arabidopsis thaliana
-
- Araújo, Ilka Schultheiß (author)
- University of Cologne
-
- Pietsch, Jessica Magdalena (author)
- University of Cologne
-
- Keizer, Emma Mathilde (author)
- Wageningen University
-
show more...
-
- Greese, Bettina (author)
- Lund University,Lunds universitet,Beräkningsbiologi och biologisk fysik - Har omorganiserats,Institutionen för astronomi och teoretisk fysik - Har omorganiserats,Naturvetenskapliga fakulteten,Computational Biology and Biological Physics - Has been reorganised,Department of Astronomy and Theoretical Physics - Has been reorganised,Faculty of Science
-
- Balkunde, Rachappa (author)
- University of Cologne
-
- Fleck, Christian (author)
- Wageningen University
-
- Hülskamp, Martin (author)
- University of Cologne
-
show less...
-
(creator_code:org_t)
- 2017-12-14
- 2017
- English.
-
In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8:1
- Related links:
-
http://dx.doi.org/10... (free)
-
show more...
-
https://www.nature.c...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Although plant development is highly reproducible, some stochasticity exists. This developmental stochasticity may be caused by noisy gene expression. Here we analyze the fluctuation of protein expression in Arabidopsis thaliana. Using the photoconvertible KikGR marker, we show that the protein expressions of individual cells fluctuate over time. A dual reporter system was used to study extrinsic and intrinsic noise of marker gene expression. We report that extrinsic noise is higher than intrinsic noise and that extrinsic noise in stomata is clearly lower in comparison to several other tissues/cell types. Finally, we show that cells are coupled with respect to stochastic protein expression in young leaves, hypocotyls and roots but not in mature leaves. Our data indicate that stochasticity of gene expression can vary between tissues/cell types and that it can be coupled in a non-cell-autonomous manner.
Subject headings
- NATURVETENSKAP -- Biologi -- Botanik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Botany (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database