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  • Johannesson, MagnusStockholm School of Economics,Handelshögskolan i Stockholm (author)

Polygenic risk scores for schizophrenia and bipolar disorder predict creativity

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2015-06-08
  • Nature Publishing Group,2015

Numbers

  • LIBRIS-ID:oai:hhs.se:1155070680006056
  • https://research.hhs.se/esploro/outputs/journalArticle/Polygenic-risk-scores-for-schizophrenia-and/991001480594806056URI
  • https://doi.org/10.1038/nn.4040DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:131523978URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity. Higher scores were associated with artistic society membership or creative profession in both Icelandic (P = 5.2 x 10(-6) and 3.8 x 10(-6) for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (P = 0.0021 and 0.00086). This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Power, Robert A.deCODE Genetics,VU University (NL) (author)
  • Steinberg, StacydeCODE Genetics (author)
  • Bjornsdottir, GydadeCODE Genetics (author)
  • Rietveld, Cornelius A.Erasmus University (NL) (author)
  • Abdellaoui, AbdelVU University (NL),Erasmus University (NL),Radboud University (NL) (author)
  • Nivard, Michel M.VU University (NL) (author)
  • Galesloot, Tessel E.Radboud University (NL) (author)
  • Hottenga, Jouke-JanVU University (NL) (author)
  • Willemsen, GonnekeVU University (NL) (author)
  • Cesarini, DavidCenter for Experimental Social Science (author)
  • Benjamin, Daniel J.Cornell University (US) (author)
  • Magnusson, Patrik K. E.Karolinska Institutet,Karolinska Institutet (SE) (author)
  • Ullén, FredrikKarolinska Institutet,Karolinska Institutet (SE) (author)
  • Tiemeier, HenningErasmus University (NL) (author)
  • Hofman, AlbertErasmus University (NL) (author)
  • Van Rooij, Frank J AErasmus University (NL) (author)
  • Walters, BragideCODE Genetics (author)
  • Sigurdsson, EngilbertUniversity of Iceland (author)
  • Thorgeirsson, Thorgeir E.deCODE Genetics (author)
  • Ingason, AndresdeCODE Genetics (author)
  • Helgason, AgnardeCODE Genetics (author)
  • Kong, AugustineUniversity of Iceland (author)
  • Kiemeney, Lambertus ARadboud University (NL) (author)
  • Koellinger, Philipp D.Erasmus School of Economics (NL) (author)
  • Boomsma, Dorret I.VU University (NL) (author)
  • Gudbjartsson, DanieldeCODE Genetics (author)
  • Stefansson, KarideCODE Genetics (author)
  • Stefansson, HreinndeCODE Genetics (author)
  • Handelshögskolan i StockholmStockholm School of Economics (creator_code:org_t)

Related titles

  • In:Nature Neuroscience: Nature Publishing Group18:7, s. 953-+1097-62561546-1726

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