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Polygenic risk scor...
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Johannesson, MagnusStockholm School of Economics,Handelshögskolan i Stockholm
(author)
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
- Article/chapterEnglish2015
Publisher, publication year, extent ...
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2015-06-08
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Nature Publishing Group,2015
Numbers
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LIBRIS-ID:oai:hhs.se:1155070680006056
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https://research.hhs.se/esploro/outputs/journalArticle/Polygenic-risk-scores-for-schizophrenia-and/991001480594806056URI
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https://doi.org/10.1038/nn.4040DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:131523978URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity. Higher scores were associated with artistic society membership or creative profession in both Icelandic (P = 5.2 x 10(-6) and 3.8 x 10(-6) for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (P = 0.0021 and 0.00086). This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.
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Power, Robert A.deCODE Genetics,VU University (NL)
(author)
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Steinberg, StacydeCODE Genetics
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Bjornsdottir, GydadeCODE Genetics
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Rietveld, Cornelius A.Erasmus University (NL)
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Abdellaoui, AbdelVU University (NL),Erasmus University (NL),Radboud University (NL)
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Nivard, Michel M.VU University (NL)
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Galesloot, Tessel E.Radboud University (NL)
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Hottenga, Jouke-JanVU University (NL)
(author)
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Willemsen, GonnekeVU University (NL)
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Cesarini, DavidCenter for Experimental Social Science
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Benjamin, Daniel J.Cornell University (US)
(author)
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Magnusson, Patrik K. E.Karolinska Institutet,Karolinska Institutet (SE)
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Ullén, FredrikKarolinska Institutet,Karolinska Institutet (SE)
(author)
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Tiemeier, HenningErasmus University (NL)
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Hofman, AlbertErasmus University (NL)
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Van Rooij, Frank J AErasmus University (NL)
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Walters, BragideCODE Genetics
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Sigurdsson, EngilbertUniversity of Iceland
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Thorgeirsson, Thorgeir E.deCODE Genetics
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Ingason, AndresdeCODE Genetics
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Helgason, AgnardeCODE Genetics
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Kong, AugustineUniversity of Iceland
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Kiemeney, Lambertus ARadboud University (NL)
(author)
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Koellinger, Philipp D.Erasmus School of Economics (NL)
(author)
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Boomsma, Dorret I.VU University (NL)
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Gudbjartsson, DanieldeCODE Genetics
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Stefansson, KarideCODE Genetics
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Stefansson, HreinndeCODE Genetics
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Handelshögskolan i StockholmStockholm School of Economics
(creator_code:org_t)
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In:Nature Neuroscience: Nature Publishing Group18:7, s. 953-+1097-62561546-1726
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Johannesson, Mag ...
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Power, Robert A.
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Steinberg, Stacy
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Abdellaoui, Abde ...
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Nivard, Michel M ...
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Galesloot, Tesse ...
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Benjamin, Daniel ...
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Magnusson, Patri ...
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Ullén, Fredrik
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Tiemeier, Hennin ...
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Hofman, Albert
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Van Rooij, Frank ...
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Walters, Bragi
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Sigurdsson, Engi ...
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Thorgeirsson, Th ...
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Ingason, Andres
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Helgason, Agnar
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Koellinger, Phil ...
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Boomsma, Dorret ...
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and Psychiatry
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Karolinska Institutet