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  • Barjesteh van Waalwijk van Doorn-Khosrovani, SaharLeiden University Medical Center (author)

PCM4EU and PRIME-ROSE : Collaboration for implementation of precision cancer medicine in Europe

  • Article/chapterEnglish2024

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  • 2024
  • electronicrdacarrier

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  • LIBRIS-ID:oai:hhs.se:1171452460006056
  • https://research.hhs.se/esploro/outputs/journalArticle/PCM4EU-and-PRIME-ROSE-Collaboration-for-implementation/991001581799606056URI
  • https://doi.org/10.2340/1651-226X.2024.34791DOI

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  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

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  • http://creativecommons.org/licenses/by/4.0/
  • BACKGROUND: In the two European Union (EU)-funded projects, PCM4EU (Personalized Cancer Medicine for all EU citizens) and PRIME-ROSE (Precision Cancer Medicine Repurposing System Using Pragmatic Clinical Trials), we aim to facilitate implementation of precision cancer medicine (PCM) in Europe by leveraging the experience from ongoing national initiatives that have already been particularly successful. PATIENTS AND METHODS: PCM4EU and PRIME-ROSE gather 17 and 24 partners, respectively, from 19 European countries. The projects are based on a network of Drug Rediscovery Protocol (DRUP)-like clinical trials that are currently ongoing or soon to start in 11 different countries, and with more trials expected to be established soon. The main aims of both the projects are to improve implementation pathways from molecular diagnostics to treatment, and reimbursement of diagnostics and tumour-tailored therapies to provide examples of best practices for PCM in Europe. RESULTS: PCM4EU and PRIME-ROSE were launched in January and July 2023, respectively. Educational materials, including a podcast series, are already available from the PCM4EU website (http://www.pcm4eu.eu). The first reports, including an overview of requirements for the reimbursement systems in participating countries and a guide on patient involvement, are expected to be published in 2024. CONCLUSION: European collaboration can facilitate the implementation of PCM and thereby provide affordable and equitable access to precision diagnostics and matched therapies for more patients. ble from the PCM4EU website (http://www.pcm4eu.eu). The first reports, including an overview of requirements for the reimbursement systems in participating countries and a guide on patient involvement, are expected to be published in 2024. CONCLUSION: European collaboration can facilitate the implementation of PCM and thereby provide affordable and equitable access to precision diagnostics and matched therapies for more patients.

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  • Taskén, KjetilOslo University Hospital (author)
  • F Haj Mohammad, SoemeyaLeiden University Medical Center (author)
  • Fagereng, Gro LiveOslo University Hospital (author)
  • Sørum Falk, RagnhildOslo University Hospital (author)
  • Helland, ÅslaugOslo University Hospital (author)
  • Jalkanen, KatriinaHelsinki University Hospital (author)
  • Edsjö, AndersSkåne University Hospital (author)
  • Russnes, Hege GOslo University Hospital (author)
  • Steen Carlsson, KatarinaSwedish Institute for Health Economics (author)
  • Ryll, BettinaStockholm School of Economics,Handelshögskolan i Stockholm(Swepub:hhs)5081@hhs.se (author)
  • Lassen, UlrikCopenhagen University Hospital (author)
  • Hallersjö Hult, EbbaStockholm School of Economics,Handelshögskolan i Stockholm (author)
  • Lugowska, IwonaMaria Curie-Skłodowska University (author)
  • Blay, Jean-YvesCentre Léon Bérard (author)
  • Verlingue, LoicCentre Léon Bérard (author)
  • Abel, EdvardUniversity of Gothenburg (author)
  • Lowery, Maeve ATrinity College Dublin (author)
  • Krebs, Matthew GThe Christie NHS Foundation Trust (author)
  • Staal Rohrberg, KristofferCopenhagen University Hospital (author)
  • Ojamaa, KristiinaTartu University Hospital (author)
  • Oliveira, JulioIPO Porto (author)
  • Verheul, Henk M WErasmus MC Cancer Institute (author)
  • Voest, Emile EThe Netherlands Cancer Institute (The Netherlands, Amsterdam) - NKI-AVL (author)
  • Gelderblom, HansLeiden University Medical Center (author)
  • Leiden University Medical CenterOslo University Hospital (creator_code:org_t)
  • PRIME-ROSE Consortium and the PCM4EU Consortium

Related titles

  • In:Acta Oncologica63, s. 385-3911651-226X1651-226X

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