Search: onr:"swepub:oai:lup.lub.lu.se:01e75cd7-35cf-4bbc-98d8-ac44cffc51c8" >
Renal arteriovenous...
Renal arteriovenous shunting in rejecting allograft, hydronephrosis, or haemorrhagic hypotension in the rat
- Article/chapterEnglish1994
Publisher, publication year, extent ...
-
1994
-
Oxford University Press (OUP),1994
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:01e75cd7-35cf-4bbc-98d8-ac44cffc51c8
-
https://lup.lub.lu.se/record/01e75cd7-35cf-4bbc-98d8-ac44cffc51c8URI
-
https://doi.org/10.1093/ndt/9.11.1634DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
We studied the occurrence of arteriovenous (A-V) shunting in three experimental rat models, namely in rejecting allograft kidney, in uni- or bilateral ureteral obstruction, and in haemorrhagic hypotension. Isografted or sham-operated rats served as controls. Radiolabelled microspheres were injected into the renal artery and the increase in the amount of radioactivity in the lungs was considered to reflect A-V shunting in the kidney. In animals exposed to haemorrhage, with a blood pressure not less than 70% of the initial blood pressure, practically no shunting was seen. When animals were bled to a hypotension beyond the autoregulation, A-V shunting occurred inversely correlated to the degree of hypotension. In ureteral obstruction, a less marked but significant increase in shunting of microspheres to the lungs was found after 24 h of unilateral obstruction, irrespective of whether the spheres were injected into the obstructed or the contralateral kidney. Significant A-V shunting during the allograft rejection process was also demonstrated. Histologically, microspheres were found in afferent arterioles less frequently in kidneys with A-V shunting than in controls. These results indicate that A-V shunting is involved in haemorrhagic hypotension, renal graft rejection, and hydronephrosis. In the latter situation A-V shunting is probably regulated by a humoral factor. © 1994 European Dialysis and Transplant Association-European Renal Association.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Ekberg, HenrikLund University,Lunds universitet,Enheten för forskning kring njurfunktion och njursjukdom,Kirurgi,Forskargrupper vid Lunds universitet,Renal Research Unit,Surgery,Lund University Research Groups(Swepub:lu)kir-hek
(author)
-
Fält, KSkåne University Hospital
(author)
-
Löfberg, HelgeLund University,Lunds universitet,Patologi, Malmö,Forskargrupper vid Lunds universitet,Pathology, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)pat-hlo
(author)
-
Sterner, GunnarLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-gst
(author)
-
Enheten för forskning kring njurfunktion och njursjukdomKirurgi
(creator_code:org_t)
Related titles
-
In:Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association: Oxford University Press (OUP)9:11, s. 1634-16391460-2385
Internet link
Find in a library
To the university's database