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Fiber-optic probe f...
Fiber-optic probe for noninvasive real-time determination of tissue optical properties at multiple wavelengths
- Article/chapterEnglish2001
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2001
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electronicrdacarrier
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LIBRIS-ID:oai:lup.lub.lu.se:0816346e-d176-4e68-876f-c78c54f72c9b
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https://lup.lub.lu.se/record/2257813URI
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https://doi.org/10.1364/AO.40.001155DOI
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
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We present a compact, fast, and versatile fiber-optic probe system for real-time determination of tissue optical properties from spatially resolved continuous-wave diffuse reflectance measurements. The system collects one set of reflectance data from six source-detector distances at four arbitrary wavelengths with a maximum overall sampling rate of 100 Hz. Multivariate calibration techniques based on two-dimensional polynomial fitting are employed to extract and display the absorption and reduced scattering coefficients in real-time mode. The four wavelengths of the current configuration are 660, 785, 805, and 974 nm, respectively. Cross-validation tests on a 6 x 7 calibration matrix of Intralipid-dye phantoms showed that the mean prediction error at, e.g., 785 nm was 2.8% for the absorption coefficient and 1.3% for the reduced scattering coefficient. The errors are relative to the range of the optical properties of the phantoms at 785 nm, which were 0-0.3/cm for the absorption coefficient and 6-16/cm for the reduced scattering coefficient. Finally, we also present and discuss results from preliminary skin tissue measurements. (C) 2001 Optical Society of America
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Pedersen, C. B
(author)
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Dalgaard, T
(author)
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Fabricius, P. E
(author)
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Aruna, P
(author)
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Andersson-Engels, StefanLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-san
(author)
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AtomfysikFysiska institutionen
(creator_code:org_t)
Related titles
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In:Applied Optics40:7, s. 1155-11642155-3165
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