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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002862naa a2200277 4500
001oai:lup.lub.lu.se:08549a33-6aa7-4209-aff2-864083acf0e4
003SwePub
008160401s2002 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/3220702 URI
024a https://doi.org/10.1016/S0165-0173(02)00198-42 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Garwicz, Martinu Lund University,Lunds universitet,Neurofysiologi,Forskargrupper vid Lunds universitet,Neurophysiology,Lund University Research Groups4 aut0 (Swepub:lu)mphy-mga
2451 0a Spinal reflexes provide motor error signals to cerebellar modules - relevance for motor coordination
264 1c 2002
520 a The cerebellar olivo-cortico-nuclear network influencing rubro- and corticospinal tracts via the nucleus interpositus anterior (NIA) is one of the most thoroughly characterized mammalian motor systems involved in limb movement control. Recent findings indicate that climbing fibres innervating the NIA system mediate highly integrated sensorimotor information derived from spinal withdrawal reflex modules. In the present paper, the implications of this relationship between spinal and cerebellar neuronal networks for cerebellar sensorimotor processing are put in perspective of the modular organization of the NIA system. Data that should prove useful for computational models of cerebellar sensorimotor processing and motor learning, including functional spino-olivo-cortico-nucleo-spinal connectivity, are reviewed. It is argued that spinal 'pre-processing' of climbing fibre input constitutes a signal conversion from 'sensory' to 'motor' coordinates, providing the cerebellar modules with motor error signals relevant to the action of single limb muscles. Drawing upon their patterns of interconnectivity with spinal reflex modules it is hypothesized how cerebellar modules may adaptively coordinate transitions between agonist and antagonist muscle activity. This mechanism would contribute to the generation of the triphasic EMG patterns that are necessary for smooth acceleration and deceleration of single-joint movements. (C) 2002 Elsevier Science B.V. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
710a Neurofysiologib Forskargrupper vid Lunds universitet4 org
773t Brain Research Reviewsg 40:1-3, s. 152-165q 40:1-3<152-165x 1872-6321
856u http://dx.doi.org/10.1016/S0165-0173(02)00198-4y FULLTEXT
8564 8u https://lup.lub.lu.se/record/322070
8564 8u https://doi.org/10.1016/S0165-0173(02)00198-4

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