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Exploring the preva...
Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies
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- Heyman, Isak (author)
- Lund University,Lunds universitet,Kognitiv sjukdomsforskning,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Cognitive disorders,Department of Clinical Sciences, Malmö,Faculty of Medicine
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- Persson, Torbjörn (author)
- Skåne University Hospital
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- Haglund, Mattias (author)
- Lund University,Lunds universitet,Patologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pathology, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Londos, Elisabet (author)
- Karolinska Institute,Lund University,Lunds universitet,Kognitiv sjukdomsforskning,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Cognitive disorders,Department of Clinical Sciences, Malmö,Faculty of Medicine
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(creator_code:org_t)
- 2023
- 2023
- English.
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In: Clinical autonomic research : official journal of the Clinical Autonomic Research Society. - 1619-1560. ; 33:4, s. 433-442
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Abstract
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- PURPOSE: To explore the prevalence of undetected bradyarrhythmia in a cohort of people with dementia with Lewy bodies.METHODS: Thirty participants diagnosed with dementia with Lewy bodies were enrolled from three memory clinics in southern Sweden between May 2021 and November 2022. None had a history of high-grade atrioventricular block or sick sinus syndrome. Each participant underwent orthostatic testing, cardiac [ 123I]metaiodobenzylguanidine scintigraphy and 24-h ambulatory electrocardiographic monitoring. Concluding bradyarrhythmia diagnosis was obtained until the end of December 2022. RESULTS: Thirteen participants (46.4%) had bradycardia at rest during orthostatic testing and four had an average heart rate < 60 beats per minute during ambulatory electrocardiographic monitoring. Three participants (10.7%) received a diagnosis of sick sinus syndrome, of whom two received pacemaker implants to manage associated symptoms. None received a diagnosis of second- or third-degree atrioventricular block.CONCLUSION: This report showed a high prevalence of sick sinus syndrome in a clinical cohort of people with dementia with Lewy bodies. Further research on the causes and consequences of sick sinus syndrome in dementia with Lewy bodies is thus warranted.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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