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Patch Testing with ...
Patch Testing with a New Composition of the Mercapto Mix - A Multicenter Study from the International Contact Dermatitis Research Group
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- Isaksson, Marléne (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Andersen, Klaus E. (author)
- Odense University Hospital
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- Cannavó, Alicia (author)
- Hospital de Clínicas "José de San Martín"
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- Elsner, Peter (author)
- Universitätsklinikum Jena
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- Goh, Chee Leok (author)
- National Skin Centre
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- Gonçalo, Margarida (author)
- University Hospital of Coimbra
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- Goossens, An (author)
- University Hospitals Leuven
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- Hadzavdic, Suzana Ljubojevic (author)
- University Hospital of Infectious Diseases
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- Pratt, Melanie (author)
- The Ottawa Hospital
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- Puangpet, Pailin (author)
- Institute of Dermatology Thailand
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- Sasseville, Denis (author)
- McGill University Health Centre, Montreal General Hospital
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- Verma, Kaushal (author)
- All India Institute of Medical Sciences
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- Bruze, Magnus (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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(creator_code:org_t)
- 2021
- 2021
- English 4 s.
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In: Dermatitis. - 1710-3568. ; 32:3, s. 160-163
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
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- Background Mercaptobenzothiazole compounds are associated with allergic contact dermatitis caused by rubber products. Several screening substances have been used for patch testing. Objective To compare the frequency of positive test reactions to a mercapto mix containing a higher concentration of 2-mercaptobenzothiazole with reactions to the combination of 2-mercaptobenzothiazole 2.0% and mercapto mix 2.0%. Methods There were 7103 dermatitis patients in 12 International Contact Dermatitis Research Group dermatology departments who were patch tested with 2-mercaptobenzothiazole 2.0% petrolatum (pet.), mercapto mix 2.0% pet., and mercapto mix 3.5% pet. Results Contact allergy to the 3 test preparations varied among the 12 centers: 2-mercaptobenzothiazole 2.0% pet. (0-2.4%), mercapto mix 2.0% pet. (0-4.9%), and mercapto mix 3.5% pet. (0-1.4%). 2-Mercaptobenzothiazole 2.0% and mercapto mix 2.0% detected a few more positive patients compared with mercapto mix 3.5%, but the difference was statistically insignificant (mercapto mix 2.0% pet., P = 1.0; 2-mercapto-benzothiazole 2.0% pet., P = 0.66). Conclusions Mercapto mix 3.5% pet. is not better than 2-mercaptobenzothiazole 2.0% and mercapto mix 2.0% by a difference that is significant. By using only 1 test preparation (mercapto mix 3.5%), an additional hapten could be tested. No cases of suspected/proven patch test sensitization were registered.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Isaksson, Marlén ...
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Andersen, Klaus ...
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Cannavó, Alicia
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Elsner, Peter
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Goh, Chee Leok
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Gonçalo, Margari ...
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Goossens, An
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Hadzavdic, Suzan ...
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Pratt, Melanie
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Puangpet, Pailin
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Sasseville, Deni ...
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Verma, Kaushal
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Bruze, Magnus
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dermatology and ...
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Dermatitis
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Lund University