Search: onr:"swepub:oai:lup.lub.lu.se:0eef268f-78ad-4421-a0dc-3554f7ed8179" > Headache in Systemi...
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000 | 05995naa a2200829 4500 | |
001 | oai:lup.lub.lu.se:0eef268f-78ad-4421-a0dc-3554f7ed8179 | |
003 | SwePub | |
008 | 160401s2013 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:127620419 | |
024 | 7 | a https://lup.lub.lu.se/record/42125432 URI |
024 | 7 | a https://doi.org/10.1002/art.381062 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1276204192 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Hanly, John G.4 aut |
245 | 1 0 | a Headache in Systemic Lupus Erythematosus Results From a Prospective, International Inception Cohort Study |
264 | c 2013-10-28 | |
264 | 1 | b Wiley,c 2013 |
520 | a ObjectiveTo examine the frequency and characteristics of headaches and their association with global disease activity and health-related quality of life (HRQOL) in patients with systemic lupus erythematosus (SLE). MethodsA disease inception cohort was assessed annually for headache (5 types) and 18 other neuropsychiatric (NP) events. Global disease activity scores (SLE Disease Activity Index 2000 [SLEDAI-2K]), damage scores (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index [SDI]), and Short Form 36 (SF-36) mental and physical component summary scores were collected. Time to first headache and associations with SF-36 scores were analyzed using Cox proportional hazards and linear regression models with generalized estimating equations. ResultsAmong the 1,732 SLE patients enrolled, 89.3% were female and 48.3% were white. The mean SD age was 34.6 +/- 13.4 years, duration of disease was 5.6 +/- 5.2 months, and length of followup was 3.8 +/- 3.1 years. At enrollment, 17.8% of patients had headache (migraine [60.7%], tension [38.6%], intractable nonspecific [7.1%], cluster [2.6%], and intracranial hypertension [1.0%]). The prevalence of headache increased to 58% after 10 years. Only 1.5% of patients had lupus headache, as identified in the SLEDAI-2K. In addition, headache was associated with other NP events attributed to either SLE or non-SLE causes. There was no association of headache with SLEDAI-2K scores (without the lupus headache variable), SDI scores, use of corticosteroids, use of antimalarials, use of immunosuppressive medications, or specific autoantibodies. SF-36 mental component scores were lower in patients with headache compared with those without headache (mean +/- SD 42.5 +/- 12.2 versus 47.8 +/- 11.3; P < 0.001), and similar differences in physical component scores were seen (38.0 +/- 11.0 in those with headache versus 42.6 +/- 11.4 in those without headache; P < 0.001). In 56.1% of patients, the headaches resolved over followup. ConclusionHeadache is frequent in SLE, but overall, it is not associated with global disease activity or specific autoantibodies. Although headaches are associated with a lower HRQOL, the majority of headaches resolve over time, independent of lupus-specific therapies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
700 | 1 | a Urowitz, Murray B.4 aut |
700 | 1 | a O'Keeffe, Aidan G.4 aut |
700 | 1 | a Gordon, Caroline4 aut |
700 | 1 | a Bae, Sang-Cheol4 aut |
700 | 1 | a Sanchez-Guerrero, Jorge4 aut |
700 | 1 | a Romero-Diaz, Juanita4 aut |
700 | 1 | a Clarke, Ann E.4 aut |
700 | 1 | a Bernatsky, Sasha4 aut |
700 | 1 | a Wallace, Daniel J.4 aut |
700 | 1 | a Ginzler, Ellen M.4 aut |
700 | 1 | a Isenberg, David A.4 aut |
700 | 1 | a Rahman, Anisur4 aut |
700 | 1 | a Merrill, Joan T.4 aut |
700 | 1 | a Petri, Michelle4 aut |
700 | 1 | a Fortin, Paul R.4 aut |
700 | 1 | a Gladman, Dafna D.4 aut |
700 | 1 | a Fessler, Barri J.4 aut |
700 | 1 | a Alarcon, Graciela S.4 aut |
700 | 1 | a Bruce, Ian N.4 aut |
700 | 1 | a Dooley, Mary Anne4 aut |
700 | 1 | a Steinsson, Kristjan4 aut |
700 | 1 | a Khamashta, Munther A.4 aut |
700 | 1 | a Ramsey-Goldman, Rosalind4 aut |
700 | 1 | a Manzi, Susan4 aut |
700 | 1 | a Sturfelt, Gunnaru Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-gst |
700 | 1 | a Nived, Olau Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-oni |
700 | 1 | a Zoma, Asad A.4 aut |
700 | 1 | a van Vollenhoven, Ronald F.u Karolinska Institutet4 aut |
700 | 1 | a Ramos-Casals, Manuel4 aut |
700 | 1 | a Aranow, Cynthia4 aut |
700 | 1 | a Mackay, Meggan4 aut |
700 | 1 | a Ruiz-Irastorza, Guillermo4 aut |
700 | 1 | a Kalunian, Kenneth C.4 aut |
700 | 1 | a Lim, S. Sam4 aut |
700 | 1 | a Inanc, Murat4 aut |
700 | 1 | a Kamen, Diane L.4 aut |
700 | 1 | a Peschken, Christine A.4 aut |
700 | 1 | a Jacobsen, Soren4 aut |
700 | 1 | a Theriault, Chris4 aut |
700 | 1 | a Thompson, Kara4 aut |
700 | 1 | a Farewell, Vernon4 aut |
710 | 2 | a Reumatologi och molekylär skelettbiologib Sektion III4 org |
773 | 0 | t Arthritis and Rheumatismd : Wileyg 65:11, s. 2887-2897q 65:11<2887-2897x 1529-0131x 0004-3591 |
856 | 4 | u http://dx.doi.org/10.1002/art.38106y FULLTEXT |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.38106 |
856 | 4 8 | u https://lup.lub.lu.se/record/4212543 |
856 | 4 8 | u https://doi.org/10.1002/art.38106 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:127620419 |
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