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Meta-analysis ident...
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
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Ellinor, Patrick T. (author)
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Lunetta, Kathryn L. (author)
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Albert, Christine M. (author)
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show more...
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Glazer, Nicole L. (author)
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Ritchie, Marylyn D. (author)
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Smith, Albert V. (author)
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Arking, Dan E. (author)
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Mueller-Nurasyid, Martina (author)
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Krijthe, Bouwe P. (author)
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Lubitz, Steven A. (author)
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Bis, Joshua C. (author)
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Chung, Mina K. (author)
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Doerr, Marcus (author)
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Ozaki, Kouichi (author)
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Roberts, Jason D. (author)
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- Smith, Gustav (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
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Pfeufer, Arne (author)
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Sinner, Moritz F. (author)
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Lohman, Kurt (author)
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Ding, Jingzhong (author)
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Smith, Nicholas L. (author)
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Smith, Jonathan D. (author)
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Rienstra, Michiel (author)
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Rice, Kenneth M. (author)
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Van Wagoner, David R. (author)
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Magnani, Jared W. (author)
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Wakili, Reza (author)
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Clauss, Sebastian (author)
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Rotter, Jerome I. (author)
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Steinbeck, Gerhard (author)
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Launer, Lenore J. (author)
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Davies, Robert W. (author)
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Borkovich, Matthew (author)
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Harris, Tamara B. (author)
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Lin, Honghuang (author)
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Voelker, Uwe (author)
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Voelzke, Henry (author)
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Milan, David J. (author)
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Hofman, Albert (author)
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Boerwinkle, Eric (author)
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Chen, Lin Y. (author)
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Soliman, Elsayed Z. (author)
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Voight, Benjamin F. (author)
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Li, Guo (author)
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Chakravarti, Aravinda (author)
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Kubo, Michiaki (author)
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Tedrow, Usha B. (author)
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Rose, Lynda M. (author)
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Ridker, Paul M. (author)
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Conen, David (author)
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Tsunoda, Tatsuhiko (author)
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Furukawa, Tetsushi (author)
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Sotoodehnia, Nona (author)
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Xu, Siyan (author)
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Kamatani, Naoyuki (author)
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Levy, Daniel (author)
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Nakamura, Yusuke (author)
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Parvez, Babar (author)
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Mahida, Saagar (author)
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Furie, Karen L. (author)
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Rosand, Jonathan (author)
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Muhammad, Raafia (author)
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Psaty, Bruce M. (author)
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Meitinger, Thomas (author)
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Perz, Siegfried (author)
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Wichmann, H-Erich (author)
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Witteman, Jacqueline C. M. (author)
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Kao, W. H. Linda (author)
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Kathiresan, Sekar (author)
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Roden, Dan M. (author)
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Uitterlinden, Andre G. (author)
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Rivadeneira, Fernando (author)
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McKnight, Barbara (author)
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- Sjögren, Marketa (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
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Newman, Anne B. (author)
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Liu, Yongmei (author)
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Gollob, Michael H. (author)
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- Melander, Olle (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
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Tanaka, Toshihiro (author)
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Stricker, Bruno H. Ch (author)
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Felix, Stephan B. (author)
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Alonso, Alvaro (author)
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Darbar, Dawood (author)
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Barnard, John (author)
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Chasman, Daniel I. (author)
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Heckbert, Susan R. (author)
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Benjamin, Emelia J. (author)
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Gudnason, Vilmundur (author)
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Kaeaeb, Stefan (author)
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(creator_code:org_t)
- 2012-04-29
- 2012
- English.
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:6, s. 88-670
- Related links:
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http://dx.doi.org/10...
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https://europepmc.or...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failure and death(1). We conducted a genome-wide association study (GWAS) in individuals of European ancestry, including 6,707 with and 52,426 without atrial fibrillation. Six new atrial fibrillation susceptibility loci were identified and replicated in an additional sample of individuals of European ancestry, including 5,381 subjects with and 10,030 subjects without atrial fibrillation (P < 5 x 10(-8)). Four of the loci identified in Europeans were further replicated in silico in a GWAS of Japanese individuals, including 843 individuals with and 3,350 individuals without atrial fibrillation. The identified loci implicate candidate genes that encode transcription factors related to cardiopulmonary development, cardiac-expressed ion channels and cell signaling molecules.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
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Ellinor, Patrick ...
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Lunetta, Kathryn ...
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Albert, Christin ...
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Glazer, Nicole L ...
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Ritchie, Marylyn ...
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Smith, Albert V.
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show more...
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Arking, Dan E.
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Mueller-Nurasyid ...
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Krijthe, Bouwe P ...
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Lubitz, Steven A ...
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Bis, Joshua C.
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Chung, Mina K.
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Doerr, Marcus
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Ozaki, Kouichi
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Roberts, Jason D ...
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Smith, Gustav
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Pfeufer, Arne
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Sinner, Moritz F ...
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Lohman, Kurt
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Ding, Jingzhong
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Smith, Nicholas ...
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Smith, Jonathan ...
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Rienstra, Michie ...
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Rice, Kenneth M.
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Van Wagoner, Dav ...
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Magnani, Jared W ...
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Wakili, Reza
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Clauss, Sebastia ...
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Rotter, Jerome I ...
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Steinbeck, Gerha ...
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Launer, Lenore J ...
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Davies, Robert W ...
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Borkovich, Matth ...
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Harris, Tamara B ...
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Lin, Honghuang
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Voelker, Uwe
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Voelzke, Henry
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Milan, David J.
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Hofman, Albert
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Boerwinkle, Eric
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Chen, Lin Y.
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Soliman, Elsayed ...
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Voight, Benjamin ...
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Li, Guo
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Chakravarti, Ara ...
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Kubo, Michiaki
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Tedrow, Usha B.
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Rose, Lynda M.
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Ridker, Paul M.
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Conen, David
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Tsunoda, Tatsuhi ...
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Furukawa, Tetsus ...
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Sotoodehnia, Non ...
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Xu, Siyan
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Kamatani, Naoyuk ...
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Levy, Daniel
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Nakamura, Yusuke
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Parvez, Babar
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Mahida, Saagar
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Furie, Karen L.
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Rosand, Jonathan
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Muhammad, Raafia
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Psaty, Bruce M.
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Meitinger, Thoma ...
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Perz, Siegfried
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Wichmann, H-Eric ...
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Witteman, Jacque ...
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Kao, W. H. Linda
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Kathiresan, Seka ...
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Roden, Dan M.
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Uitterlinden, An ...
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Rivadeneira, Fer ...
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McKnight, Barbar ...
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Sjögren, Marketa
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Newman, Anne B.
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Liu, Yongmei
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Gollob, Michael ...
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Melander, Olle
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Tanaka, Toshihir ...
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Stricker, Bruno ...
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Felix, Stephan B ...
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Alonso, Alvaro
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Darbar, Dawood
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Barnard, John
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Chasman, Daniel ...
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Heckbert, Susan ...
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Benjamin, Emelia ...
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Gudnason, Vilmun ...
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Kaeaeb, Stefan
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Nature Genetics
- By the university
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Lund University