Search: onr:"swepub:oai:lup.lub.lu.se:1386705e-775a-44a0-945b-85da0b7d77fd" > Breakprone chromoso...
Fältnamn | Indikatorer | Metadata |
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000 | 03438naa a2200373 4500 | |
001 | oai:lup.lub.lu.se:1386705e-775a-44a0-945b-85da0b7d77fd | |
003 | SwePub | |
008 | 181218s1988 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/1386705e-775a-44a0-945b-85da0b7d77fd2 URI |
024 | 7 | a https://doi.org/10.1111/j.1601-5223.1988.tb00193.x2 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a JOHANSSON, BERTILu Lund University,Lunds universitet,Avdelningen för klinisk genetik,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Clinical Genetics,Department of Laboratory Medicine,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)kgen-bjo |
245 | 1 0 | a Breakprone chromosome bands in fibroblasts from patients with non‐Hodgkin's lymphoma do not coincide with bands involved in primary rearrangements in non‐Hodgkin's lymphomas |
264 | c 2008-02-14 | |
264 | 1 | b Springer Science and Business Media LLC,c 1988 |
520 | a The distribution of breakpoints in structural chromosome aberrations (chromatid and chromosome gaps, breaks, and exchanges) was studied in skin fibroblasts from 35 untreated patients with non‐Hodgkin's lymphoma (NHL) and 39 controls. A total of 227 aberrations in the NHL group and 260 in the control group could be assigned to specific chromosome bands. The distribution of breakpoints was nonrandom in both groups (p<0.001), with excessive breakage in 17 bands among the NHL patients and in 21 among the controls. Two of the hot spots in the NHL group (6q21,14q24) and three in the control group (2q33,6q21, 6q25) coincided with the 60 chromosome bands that are targets for primary chromosome abnormalities in NHL. We conclude that the chromosome bands involved in primary structural abnormalities in lymphoma cells are not constitutionally breakprone in NHL patients. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
700 | 1 | a MERTENS, FREDRIKu Skåne University Hospital4 aut0 (Swepub:lu)kgen-fme |
700 | 1 | a HEIM, SVERREu Skåne University Hospital4 aut0 (Swepub:lu)klin-she |
700 | 1 | a KRISTOFFERSSON, ULFu Skåne University Hospital4 aut0 (Swepub:lu)kgen-ukr |
700 | 1 | a MANDAHL, NILSu Skåne University Hospital4 aut0 (Swepub:lu)kgen-nma |
700 | 1 | a OLSSON, HAKANu Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)onk-hol |
700 | 1 | a MITELMAN, FELIXu Skåne University Hospital4 aut0 (Swepub:lu)kgen-fmi |
710 | 2 | a Avdelningen för klinisk genetikb Institutionen för laboratoriemedicin4 org |
773 | 0 | t Hereditasd : Springer Science and Business Media LLCg 109:1, s. 131-137q 109:1<131-137x 0018-0661 |
856 | 4 | u http://dx.doi.org/10.1111/j.1601-5223.1988.tb00193.xy FULLTEXT |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1601-5223.1988.tb00193.x |
856 | 4 8 | u https://lup.lub.lu.se/record/1386705e-775a-44a0-945b-85da0b7d77fd |
856 | 4 8 | u https://doi.org/10.1111/j.1601-5223.1988.tb00193.x |
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