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Adolescents and young adults (AYA) with cancer : a position paper from the AYA Working Group of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE)

Ferrari, A. (author)
Istituto Nazionale dei Tumori
Stark, D. (author)
Leeds School of Medicine
Peccatori, F. A. (author)
European Institute of Oncology
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Fern, L. (author)
University College London Hospital
Laurence, V. (author)
Curie Institute, Paris
Gaspar, N. (author)
Institut Gustave Roussy
Bozovic-Spasojevic, I. (author)
Institute for Oncology and Radiology of Serbia (IORS)
Smith, O. (author)
University College Dublin
De Munter, J. (author)
Ghent University Hospital
Derwich, K. (author)
Poznan University of Medical Sciences
Hjorth, L. (author)
Lund University,Lunds universitet,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Late effects after childhood cancer treatment,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments
van der Graaf, W. T.A. (author)
Netherlands Cancer Institute
Soanes, L. (author)
Teenage Cancer Trust
Jezdic, S. (author)
European Society of Medical Oncology (ESMO)
Blondeel, A. (author)
The European Society of Paediatric Oncology (SIOPE)
Bielack, S. (author)
Klinikum Stuttgart Olgahospital
Douillard, J. Y. (author)
European Society of Medical Oncology (ESMO)
Mountzios, G. (author)
Henry Dunant Hospital
Saloustros, E. (author)
University Hospital of Larissa
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 (creator_code:org_t)
Elsevier BV, 2021
2021
English.
In: ESMO Open. - : Elsevier BV. - 2059-7029. ; 6:2
  • Research review (peer-reviewed)
Abstract Subject headings
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  • It is well recognised that adolescents and young adults (AYA) with cancer have inequitable access to oncology services that provide expert cancer care and consider their unique needs. Subsequently, survival gains in this patient population have improved only modestly compared with older adults and children with cancer. In 2015, the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE) established the joint Cancer in AYA Working Group in order to increase awareness among adult and paediatric oncology communities, enhance knowledge on specific issues in AYA and ultimately improve the standard of care for AYA with cancer across Europe. This manuscript reflects the position of this working group regarding current AYA cancer care, the challenges to be addressed and possible solutions. Key challenges include the lack of specific biological understanding of AYA cancers, the lack of access to specialised centres with age-appropriate multidisciplinary care and the lack of available clinical trials with novel therapeutics. Key recommendations include diversifying interprofessional cooperation in AYA care and specific measures to improve trial accrual, including centralising care where that is the best means to achieve trial accrual. This defines a common vision that can lead to improved outcomes for AYA with cancer in Europe.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

adolescents and young adults
cancer
clinical trials
education
interdisciplinary

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