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Meandering nanochan...
Meandering nanochannels for imaging of ultra-long DNA molecules
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- Freitag, C. (author)
- University of Gothenburg
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- Fritzsche, J. (author)
- University of Gothenburg
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- Persson, F. (author)
- University of Gothenburg
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- Mir, Kalim U. (author)
- University of Oxford
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- Tegenfeldt, J. O. (author)
- University of Gothenburg,Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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(creator_code:org_t)
- 2011
- 2011
- English 3 s.
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In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. - 9781618395955 ; 3, s. 1758-1760
- Related links:
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https://lup.lub.lu.s...
Abstract
Subject headings
Close
- A new chip design for handling and studying chromosomal DNA is described. Folding the nanochannels enables us to image an entire yeast chromosome in a single field of view. Together with existing mapping techniques our new design opens up the possibility of directly analyzing entire chromosomes in a single field of view using fluorescence microscopy. This would enable, for example, identification of microorganisms on a single-cell basis and the complete physical mapping of the human genome, chromosome by chromosome.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
- NATURVETENSKAP -- Biologi -- Cellbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Cell Biology (hsv//eng)
Keyword
- Chromosomal DNA
- DNA analysis
- Genomics
- Nanofluidics
Publication and Content Type
- kon (subject category)
- ref (subject category)
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