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Genetic loci influe...
Genetic loci influencing kidney function and chronic kidney disease
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Chambers, John C. (author)
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Zhang, Weihua (author)
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Lord, Graham M. (author)
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show more...
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van der Harst, Pim (author)
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Lawlor, Debbie A. (author)
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Sehmi, Joban S. (author)
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Gale, Daniel P. (author)
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Wass, Mark N. (author)
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Ahmadi, Kourosh R. (author)
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Bakker, Stephan J. L. (author)
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Beckmann, Jacqui (author)
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Bilo, Henk J. G. (author)
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Bochud, Murielle (author)
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Brown, Morris J. (author)
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Caulfield, Mark J. (author)
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Connell, John M. C. (author)
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Cook, H. Terence (author)
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Cotlarciuc, Ioana (author)
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Smith, George Davey (author)
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de Silva, Ranil (author)
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Deng, Guohong (author)
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Devuyst, Olivier (author)
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Dikkeschei, Lambert D. (author)
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Dimkovic, Nada (author)
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Dockrell, Mark (author)
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Dominiczak, Anna (author)
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Ebrahim, Shah (author)
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Eggermann, Thomas (author)
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Farrall, Martin (author)
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Ferrucci, Luigi (author)
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Floege, Jurgen (author)
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Forouhi, Nita G. (author)
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Gansevoort, Ron T. (author)
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Han, Xijin (author)
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- Hedblad, Bo (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
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van der Heide, Jaap J. Homan (author)
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Hepkema, Bouke G. (author)
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Hernandez-Fuentes, Maria (author)
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Hypponen, Elina (author)
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Johnson, Toby (author)
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de Jong, Paul E. (author)
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Kleefstra, Nanne (author)
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Lagou, Vasiliki (author)
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Lapsley, Marta (author)
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Li, Yun (author)
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Loos, Ruth J. F. (author)
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Luan, Jian'an (author)
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- Luttropp, Karin (author)
- Karolinska Institutet
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Marechal, Celine (author)
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- Melander, Olle (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
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Munroe, Patricia B. (author)
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- Nordfors, Louise (author)
- Karolinska Institutet
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Parsa, Afshin (author)
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Peltonen, Leena (author)
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Penninx, Brenda W. (author)
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Perucha, Esperanza (author)
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Pouta, Anneli (author)
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Prokopenko, Inga (author)
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Roderick, Paul J. (author)
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Ruokonen, Aimo (author)
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Samani, Nilesh J. (author)
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Sanna, Serena (author)
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- Schalling, Martin (author)
- Karolinska Institutet
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Schlessinger, David (author)
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Schlieper, Georg (author)
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Seelen, Marc A. J. (author)
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Shuldiner, Alan R. (author)
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- Sjögren, Marketa (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - hypertoni,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Cardiovascular Research - Hypertension
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Smit, Johannes H. (author)
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Snieder, Harold (author)
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Soranzo, Nicole (author)
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Spector, Timothy D. (author)
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- Stenvinkel, Peter (author)
- Karolinska Institutet
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Sternberg, Michael J. E. (author)
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Swaminathan, Ramasamyiyer (author)
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Tanaka, Toshiko (author)
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Ubink-Veltmaat, Lielith J. (author)
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Uda, Manuela (author)
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Vollenweider, Peter (author)
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Wallace, Chris (author)
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Waterworth, Dawn (author)
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Zerres, Klaus (author)
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Waeber, Gerard (author)
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Wareham, Nicholas J. (author)
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Maxwell, Patrick H. (author)
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McCarthy, Mark I. (author)
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Jarvelin, Marjo-Riitta (author)
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Mooser, Vincent (author)
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Abecasis, Goncalo R. (author)
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Lightstone, Liz (author)
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Scott, James (author)
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Navis, Gerjan (author)
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Elliott, Paul (author)
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Kooner, Jaspal S. (author)
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(creator_code:org_t)
- 2010-04-11
- 2010
- English.
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 42:5, s. 373-375
- Related links:
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http://dx.doi.org/10...
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https://europepmc.or...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
Close
- Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into metabolic, solute and drug-transport pathways underlying susceptibility to chronic kidney disease.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
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Chambers, John C ...
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Zhang, Weihua
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Lord, Graham M.
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van der Harst, P ...
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Lawlor, Debbie A ...
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Sehmi, Joban S.
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show more...
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Gale, Daniel P.
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Wass, Mark N.
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Ahmadi, Kourosh ...
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Bakker, Stephan ...
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Beckmann, Jacqui
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Bilo, Henk J. G.
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Bochud, Murielle
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Brown, Morris J.
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Caulfield, Mark ...
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Connell, John M. ...
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Cook, H. Terence
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Cotlarciuc, Ioan ...
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Smith, George Da ...
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de Silva, Ranil
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Deng, Guohong
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Devuyst, Olivier
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Dikkeschei, Lamb ...
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Dimkovic, Nada
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Dockrell, Mark
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Dominiczak, Anna
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Ebrahim, Shah
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Eggermann, Thoma ...
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Farrall, Martin
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Ferrucci, Luigi
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Floege, Jurgen
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Forouhi, Nita G.
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Gansevoort, Ron ...
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Han, Xijin
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Hedblad, Bo
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van der Heide, J ...
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Hepkema, Bouke G ...
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Hernandez-Fuente ...
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Hypponen, Elina
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Johnson, Toby
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de Jong, Paul E.
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Kleefstra, Nanne
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Lagou, Vasiliki
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Lapsley, Marta
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Li, Yun
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Loos, Ruth J. F.
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Luan, Jian'an
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Luttropp, Karin
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Marechal, Celine
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Melander, Olle
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Munroe, Patricia ...
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Nordfors, Louise
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Parsa, Afshin
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Peltonen, Leena
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Penninx, Brenda ...
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Perucha, Esperan ...
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Pouta, Anneli
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Prokopenko, Inga
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Roderick, Paul J ...
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Ruokonen, Aimo
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Samani, Nilesh J ...
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Sanna, Serena
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Schalling, Marti ...
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Schlessinger, Da ...
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Schlieper, Georg
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Seelen, Marc A. ...
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Shuldiner, Alan ...
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Sjögren, Marketa
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Smit, Johannes H ...
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Snieder, Harold
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Soranzo, Nicole
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Spector, Timothy ...
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Stenvinkel, Pete ...
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Sternberg, Micha ...
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Swaminathan, Ram ...
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Tanaka, Toshiko
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Ubink-Veltmaat, ...
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Uda, Manuela
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Vollenweider, Pe ...
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Wallace, Chris
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Waterworth, Dawn
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Zerres, Klaus
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Waeber, Gerard
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Wareham, Nichola ...
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Maxwell, Patrick ...
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McCarthy, Mark I ...
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Jarvelin, Marjo- ...
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Mooser, Vincent
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Abecasis, Goncal ...
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Lightstone, Liz
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Scott, James
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Navis, Gerjan
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Elliott, Paul
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Kooner, Jaspal S ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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Nature Genetics
- By the university
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Lund University
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Karolinska Institutet