Search: onr:"swepub:oai:lup.lub.lu.se:19f98906-09b8-4ccd-8d8f-b7f361c16278" >
Genetic loci influe...
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Chambers, John C.
(author)
Genetic loci influencing kidney function and chronic kidney disease
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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2010-04-11
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Springer Science and Business Media LLC,2010
Numbers
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LIBRIS-ID:oai:lup.lub.lu.se:19f98906-09b8-4ccd-8d8f-b7f361c16278
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https://lup.lub.lu.se/record/1619028URI
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https://doi.org/10.1038/ng.566DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:120375065URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into metabolic, solute and drug-transport pathways underlying susceptibility to chronic kidney disease.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Zhang, Weihua
(author)
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Lord, Graham M.
(author)
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van der Harst, Pim
(author)
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Lawlor, Debbie A.
(author)
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Sehmi, Joban S.
(author)
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Gale, Daniel P.
(author)
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Wass, Mark N.
(author)
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Ahmadi, Kourosh R.
(author)
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Bakker, Stephan J. L.
(author)
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Beckmann, Jacqui
(author)
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Bilo, Henk J. G.
(author)
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Bochud, Murielle
(author)
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Brown, Morris J.
(author)
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Caulfield, Mark J.
(author)
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Connell, John M. C.
(author)
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Cook, H. Terence
(author)
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Cotlarciuc, Ioana
(author)
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Smith, George Davey
(author)
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de Silva, Ranil
(author)
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Deng, Guohong
(author)
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Devuyst, Olivier
(author)
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Dikkeschei, Lambert D.
(author)
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Dimkovic, Nada
(author)
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Dockrell, Mark
(author)
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Dominiczak, Anna
(author)
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Ebrahim, Shah
(author)
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Eggermann, Thomas
(author)
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Farrall, Martin
(author)
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Ferrucci, Luigi
(author)
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Floege, Jurgen
(author)
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Forouhi, Nita G.
(author)
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Gansevoort, Ron T.
(author)
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Han, Xijin
(author)
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Hedblad, BoLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups(Swepub:lu)medf-bhe
(author)
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van der Heide, Jaap J. Homan
(author)
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Hepkema, Bouke G.
(author)
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Hernandez-Fuentes, Maria
(author)
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Hypponen, Elina
(author)
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Johnson, Toby
(author)
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de Jong, Paul E.
(author)
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Kleefstra, Nanne
(author)
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Lagou, Vasiliki
(author)
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Lapsley, Marta
(author)
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Li, Yun
(author)
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Loos, Ruth J. F.
(author)
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Luan, Jian'an
(author)
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Luttropp, KarinKarolinska Institutet
(author)
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Marechal, Celine
(author)
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Melander, OlleLund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups(Swepub:lu)endo-ome
(author)
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Munroe, Patricia B.
(author)
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Nordfors, LouiseKarolinska Institutet
(author)
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Parsa, Afshin
(author)
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Peltonen, Leena
(author)
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Penninx, Brenda W.
(author)
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Perucha, Esperanza
(author)
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Pouta, Anneli
(author)
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Prokopenko, Inga
(author)
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Roderick, Paul J.
(author)
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Ruokonen, Aimo
(author)
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Samani, Nilesh J.
(author)
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Sanna, Serena
(author)
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Schalling, MartinKarolinska Institutet
(author)
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Schlessinger, David
(author)
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Schlieper, Georg
(author)
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Seelen, Marc A. J.
(author)
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Shuldiner, Alan R.
(author)
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Sjögren, MarketaLund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - hypertoni,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Cardiovascular Research - Hypertension(Swepub:lu)endo-msj
(author)
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Smit, Johannes H.
(author)
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Snieder, Harold
(author)
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Soranzo, Nicole
(author)
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Spector, Timothy D.
(author)
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Stenvinkel, PeterKarolinska Institutet
(author)
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Sternberg, Michael J. E.
(author)
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Swaminathan, Ramasamyiyer
(author)
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Tanaka, Toshiko
(author)
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Ubink-Veltmaat, Lielith J.
(author)
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Uda, Manuela
(author)
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Vollenweider, Peter
(author)
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Wallace, Chris
(author)
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Waterworth, Dawn
(author)
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Zerres, Klaus
(author)
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Waeber, Gerard
(author)
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Wareham, Nicholas J.
(author)
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Maxwell, Patrick H.
(author)
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McCarthy, Mark I.
(author)
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Jarvelin, Marjo-Riitta
(author)
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Mooser, Vincent
(author)
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Abecasis, Goncalo R.
(author)
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Lightstone, Liz
(author)
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Scott, James
(author)
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Navis, Gerjan
(author)
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Elliott, Paul
(author)
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Kooner, Jaspal S.
(author)
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Kardiovaskulär forskning - epidemiologiForskargrupper vid Lunds universitet
(creator_code:org_t)
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In:Nature Genetics: Springer Science and Business Media LLC42:5, s. 373-3751546-17181061-4036
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- By the author/editor
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Chambers, John C ...
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Zhang, Weihua
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Lord, Graham M.
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van der Harst, P ...
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Lawlor, Debbie A ...
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Sehmi, Joban S.
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show more...
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Gale, Daniel P.
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Wass, Mark N.
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Ahmadi, Kourosh ...
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Bakker, Stephan ...
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Beckmann, Jacqui
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Bilo, Henk J. G.
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Bochud, Murielle
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Brown, Morris J.
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Caulfield, Mark ...
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Connell, John M. ...
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Cook, H. Terence
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Cotlarciuc, Ioan ...
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Smith, George Da ...
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de Silva, Ranil
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Deng, Guohong
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Devuyst, Olivier
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Dikkeschei, Lamb ...
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Dimkovic, Nada
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Dockrell, Mark
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Dominiczak, Anna
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Ebrahim, Shah
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Eggermann, Thoma ...
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Farrall, Martin
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Ferrucci, Luigi
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Floege, Jurgen
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Forouhi, Nita G.
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Gansevoort, Ron ...
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Han, Xijin
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Hedblad, Bo
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van der Heide, J ...
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Hepkema, Bouke G ...
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Hernandez-Fuente ...
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Hypponen, Elina
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Johnson, Toby
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de Jong, Paul E.
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Kleefstra, Nanne
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Lagou, Vasiliki
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Lapsley, Marta
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Li, Yun
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Loos, Ruth J. F.
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Luan, Jian'an
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Luttropp, Karin
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Marechal, Celine
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Melander, Olle
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Munroe, Patricia ...
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Nordfors, Louise
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Parsa, Afshin
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Peltonen, Leena
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Perucha, Esperan ...
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Prokopenko, Inga
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Roderick, Paul J ...
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Ruokonen, Aimo
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Samani, Nilesh J ...
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Schalling, Marti ...
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Schlessinger, Da ...
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Schlieper, Georg
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Seelen, Marc A. ...
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Sjögren, Marketa
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Smit, Johannes H ...
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Soranzo, Nicole
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Sternberg, Micha ...
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Swaminathan, Ram ...
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Tanaka, Toshiko
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Zerres, Klaus
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McCarthy, Mark I ...
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Jarvelin, Marjo- ...
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- MEDICAL AND HEALTH SCIENCES
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Nature Genetics
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Lund University
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Karolinska Institutet