Gut barrier failure in critical illness: lessons learned from acute pancreatitis

• Gut barrier function is essential in critical illness and contributes to the systemic inflammatory response. Failure of the gut barrier includes both changes in microbial ecology, permeability and potential translocation, as well as local gut inflammatory response. The present review summarizes experiences made from acute pancreatitis, including pathophysiological mechanisms and ways of intervention.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Critical illness

acute pancreatitis

gut barrier failure

SIRS

MODS

Publication and Content Type

art (subject category)

ref (subject category)