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Antioxidant seconda...
Antioxidant secondary metabolites from Geranium lasiopus Boiss. & Heldr.
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Sohretoglu, Didem (author)
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Sakar, Mahmut Koray (author)
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Sabuncuoglu, Suna Atasayar (author)
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Ozgunes, Hilal (author)
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Duman, Hayri (author)
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- Sterner, Olov (author)
- Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
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(creator_code:org_t)
- Informa UK Limited, 2012
- 2012
- English.
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In: Natural Product Research. - : Informa UK Limited. - 1478-6419 .- 1478-6427. ; 26:13, s. 1261-1264
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Chromatographic studies on the EtOAc soluble portion of the MeOH extract of Geranium lasiopus led to the isolation of eight flavonoids (kaempferol (1), quercetin (2), quercetin 3-O-beta-glucopyranoside (3), quercetin 3-O-beta-galactopyranoside (4), kaempferol 3-O-alpha-rhamnopyranosyl-(1 -> 6)-beta-glucopyranoside (5), quercetin 3-O-alpha-rhamnopyranosyl-(1 -> 6)-beta-glucopyranoside (6), kaempferol 3-O-alpha-rhamnopyranosyl-(1 -> 2)-beta-glucopyranoside (7) and quercetin 3-O-alpha-rhamnopyranosyl-(1 -> 2)-beta-glucopyranoside (8)), two simple phenolic compounds (gallic acid (9) and its methyl ester (10)) and a hydrolysable tannin (pusilagin (11)). The structures of the compounds were elucidated by 1- and 2-dimensional NMR techniques (H-1, C-13, COSY, HMBC, HMQC) and ESI-TOF-MS spectrometry. Inhibitory effects on H2O2-induced lipid peroxidation in human red blood cells of the different extracts of G. lasiopus, as well as isolated compounds, were investigated. All tested compounds showed comparable or higher activity than that of ascorbic acid and trolox.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Keyword
- Geranium lasiopus
- Geraniaceae
- flavonoids
- tannin
- antioxidant activity
Publication and Content Type
- art (subject category)
- ref (subject category)
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