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Risk factors and in...
Risk factors and incidence of new-onset heart failure with conventional pacemakerimplant – a nationwide study
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- Farouq, Maiwand (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Rorsman Schough, Cecilia (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Hallands sjukhus, Varberg
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- Marinko, Sofia (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Mortsell, David (author)
- Lund University,Lunds universitet,Arrhytmias and Cardiac Device treatment,Forskargrupper vid Lunds universitet,Electrocardiology Research Group - CIEL,Lund University Research Groups
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- Chaudhry, Uzma (author)
- Lund University,Lunds universitet,Arrhytmias and Cardiac Device treatment,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Wang, Lingwei (author)
- Lund University,Lunds universitet,Arrhytmias and Cardiac Device treatment,Forskargrupper vid Lunds universitet,Clinical studies af Atrial Fibrillation,Lund University Research Groups
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- Platonov, Pyotr (author)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Borgquist, Rasmus (author)
- Lund University,Lunds universitet,Arrhytmias and Cardiac Device treatment,Forskargrupper vid Lunds universitet,Electrocardiology Research Group - CIEL,Clinical studies af Atrial Fibrillation,Lund University Research Groups
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(creator_code:org_t)
- 2024
- 2024
- English.
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In: Heart Rhythm O2. - 2666-5018.
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Abstract
Subject headings
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- BackgroundStudies have shown that the risk of new-onset heart failure (HF) is higher post-implant for patients receiving right ventricular pacing.ObjectiveThis study aimed to investigate incidence, risk factors and implications for long-term prognosis of new-onset HF in patients after pacemaker-implant.MethodsPatients without preexisting HF who received a pacemaker in Sweden during the period 2005-2020 were identified via the nationwide Pacemaker Registry. Data was crossmatched with the population registry and national disease registries. Primary outcome was new-onset HF within 5 years, and a risk score for this was developed and validated..ResultsIn all, 65579 patients met the inclusion criteria (10351 single chamber ventricular and 55228 dual chamber pacemakers). 13792 (21.0%) patients were diagnosed with HF within five years post-implant. Of these, 6244 (45.3%) were hospitalized for HF. Patients with new-onset heart failure were more likely to die within five years (41.2% vs. 19.7%, p<0.0001). Risk factors for new-onset HF included increasing age, male sex, hypertension, diabetes, atrial fibrillation, chronic lung- and kidney disease, ischemic heart disease, and AV block. In a combined score using these variables, patients in the highest risk-score quartile had a hazard ratio of 5.36 [4.91-5.86] (p<0.001) and an absolute risk of 32% for developing HF.ConclusionPacemaker therapy is associated with >20% risk of new-onset HF within five years, and we identified nine risk factors associated with the diagnosis of new-onset HF. The proposed score based on these variables can be used to identify patients at high risk for new-onset heart failure
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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