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Low molecular weigh...
Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis
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Bergqvist, D (author)
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- Mätzsch, Thomas (author)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Burmark, U S (author)
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Frisell, J (author)
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Guilbaud, O (author)
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Hallbook, T (author)
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Horn, A (author)
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Lindhagen, A (author)
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Ljungner, H (author)
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Ljungstrom, K G (author)
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(creator_code:org_t)
- 2005-12-06
- 1988
- English.
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In: British Journal of Surgery. - : Oxford University Press (OUP). - 1365-2168 .- 0007-1323. ; 75:9, s. 888-891
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A prospective randomized double-blind trial was performed comparing conventional low-dose heparin with a low molecular weight heparin fragment for thromboprophylaxis in elective general abdominal surgical patients. The first dose of the heparin fragment was given the evening before surgery, and further doses were given thereafter every evening. There were 1002 analysable patients, 826 having received correct prophylaxis. Of these 1002 patients, 64 per cent were operated on for malignant disease. A total of 20 patients died, 10 in each group. The frequency of deep vein thrombosis was significantly reduced among patients with correct prophylaxis with the heparin fragment (9.2-5.0 per cent, P = 0.02) [corrected]. The frequency of bleeding was 6.7 per cent among the heparin fragment patients and 2.7 per cent among the patients given conventional heparin (P = 0.01), but all bleeds were of minor degree and there was no difference in the reoperation rate for bleeding, or in the transfusion requirements. Local pain at the injection site was reported significantly less often among patients given the heparin fragment.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Low molecular weight heparin
- low dose heparin
- postoperative thrombo-embolism
- prophylaxis
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Bergqvist, D
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Mätzsch, Thomas
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Burmark, U S
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Frisell, J
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Guilbaud, O
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Hallbook, T
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show more...
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Horn, A
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Lindhagen, A
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Ljungner, H
-
Ljungstrom, K G
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
- Articles in the publication
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British Journal ...
- By the university
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Lund University