No increase in fracture incidence in patients treated for thyrotoxicosis in Malmo during 1970-74. A 20-year population-based follow-up

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Hallengren, BengtSkåne University Hospital (author)

No increase in fracture incidence in patients treated for thyrotoxicosis in Malmo during 1970-74. A 20-year population-based follow-up

Article/chapterEnglish1999

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Wiley,1999

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LIBRIS-ID:oai:lup.lub.lu.se:27fbf096-0f79-4718-9cd8-005c333bfc52
https://lup.lub.lu.se/record/27fbf096-0f79-4718-9cd8-005c333bfc52URI
https://doi.org/10.1046/j.1365-2796.1999.00497.xDOI

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Language:English
Summary in:English

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Objectives. To study whether there is an increased fracture incidence following thyrotoxicosis. Design. A case-control study. Setting. Malmo University Hospital, Malmo, Sweden. Subjects: All patients (n = 333) from the population of Malmo who were treated for thyrotoxicosis for the first time during the 5-year period 1970-74. A total of 618 controls were selected from the local municipality registry in Malmo. For each case the aim was to randomly select two age- and gender-specific controls, alive in 1993 and born the same year and month as the case. Main outcome measures. Fracture incidence. Results. Comparing survivors, there were no differences in the percentage of individuals with fractures (all, fragility, non-fragility) between the patients and the controls. Comparing all individuals and including all fractures, the percentage of individuals with fractures in the entire female patient group (24.6%) was lower (P < 0.05) than in female controls (33.1%). There was a similar but non-significant pattern between male patients and controls. The mean number of all fractures was lower in male patients than in controls (P < 0.05), but no significant difference was noted between female patients and controls. For fragility fractures, there were no significant differences in the percentage of individuals with fractures or in the mean number of fractures between female or male patients and controls. Conclusion. In conclusion we found no increased incidence of fragility fractures in patients with previous thyrotoxicosis as compared with controls. Our results do not support the suggestion that screening for osteoporosis should be performed in patients with previous thyrotoxicosis.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Geriatrik hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Geriatrics hsv//eng
Fracture
Fragility fracture
Graves' disease
Thyrotoxicosis

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Elmståhl, BarbaraSkåne University Hospital(Swepub:lu)ront-bel (author)
Berglund, J.Skåne University Hospital(Swepub:lu)smi-jbe (author)
Christensen, S. B.Skåne University Hospital (author)
Elmståhl, S.Skåne University Hospital(Swepub:lu)smi-sel (author)
Johnell, O.Skåne University Hospital(Swepub:lu)orto-ojo (author)
Thorngren, K. G.Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Reumatologi och molekylär skelettbiologi,Institutionen för kliniska vetenskaper, Lund,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Rheumatology,Department of Clinical Sciences, Lund,Skåne University Hospital(Swepub:lu)ort-kgth (author)
Skåne University HospitalOrtopedi, Lund (creator_code:org_t)

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In:Journal of Internal Medicine: Wiley246:2, s. 139-1440954-68201365-2796

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