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Towards clinical gr...
Towards clinical grating-interferometry mammography
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- Arboleda, Carolina (author)
- ETH Zürich,Paul Scherrer Institute
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- Wang, Zhentian (author)
- ETH Zürich,Paul Scherrer Institute
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- Jefimovs, Konstantins (author)
- ETH Zürich,Paul Scherrer Institute
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Koehler, Thomas (author)
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Van Stevendaal, Udo (author)
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Kuhn, Norbert (author)
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David, Bernd (author)
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Prevrhal, Sven (author)
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- Lång, Kristina (author)
- Lund University,Lunds universitet,ETH Zürich,Paul Scherrer Institute
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- Forte, Serafino (author)
- Hospital Baden
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- Kubik-Huch, Rahel Antonia (author)
- Hospital Baden
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Leo, Cornelia (author)
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- Singer, Gad (author)
- Hospital Baden
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- Marcon, Magda (author)
- University Hospital of Zurich
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- Boss, Andreas (author)
- University Hospital of Zurich
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Roessl, Ewald (author)
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- Stampanoni, Marco (author)
- Paul Scherrer Institute,ETH Zürich
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(creator_code:org_t)
- 2019-08-22
- 2019
- English.
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In: European Radiology. - : Springer Science and Business Media LLC. - 0938-7994 .- 1432-1084. ; , s. 1-7
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Abstract
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- Objectives: Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, as several research works have demonstrated in a pre-clinical setting, since it is able to provide attenuation, differential phase contrast, and scattering images simultaneously. In order to translate this technique to the clinics, it has to be adapted to cover a large field-of-view within a clinically acceptable exposure time and radiation dose. Methods: We set up a grating interferometer that fits into a standard mammography system and fulfilled the aforementioned conditions. Here, we present the first mastectomy images acquired with this experimental device. Results and conclusion: Our system performs at a mean glandular dose of 1.6 mGy for a 5-cm-thick, 18%-dense breast, and a field-of-view of 26 × 21 cm2. It seems to be well-suited as basis for a clinical-environment device. Further, dark-field signals seem to support an improved lesion visualization. Evidently, the effective impact of such indications must be evaluated and quantified within the context of a proper reader study. Key Points: • Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, since it is sensitive to refraction and scattering and thus provides additional tissue information. • The most straightforward way to do grating-interferometry in the clinics is to modify a standard mammography device. • In a first approximation, the doses given with this technique seem to be similar to those of conventional mammography.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- Interferometry
- Mammography
- Phase contrast
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Arboleda, Caroli ...
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Wang, Zhentian
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Jefimovs, Konsta ...
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Koehler, Thomas
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Van Stevendaal, ...
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Kuhn, Norbert
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show more...
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David, Bernd
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Prevrhal, Sven
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Lång, Kristina
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Forte, Serafino
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Kubik-Huch, Rahe ...
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Leo, Cornelia
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Singer, Gad
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Marcon, Magda
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Boss, Andreas
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Roessl, Ewald
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Stampanoni, Marc ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Radiology Nuclea ...
- Articles in the publication
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European Radiolo ...
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Lund University