Search: onr:"swepub:oai:lup.lub.lu.se:287b58fb-4e9f-4d28-923f-35a1b83fbb43" >
Core Lab Adjudicati...
-
Elkoumy, AhmedGalway University Hospital
(author)
Core Lab Adjudication of the ACURATE neo2 Hemodynamic Performance Using Computed-Tomography-Corrected Left Ventricular Outflow Tract Area
- Article/chapterEnglish2022
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:287b58fb-4e9f-4d28-923f-35a1b83fbb43
-
https://lup.lub.lu.se/record/287b58fb-4e9f-4d28-923f-35a1b83fbb43URI
-
https://doi.org/10.3390/jcm11206103DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:151067964URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
(1) Background: Hemodynamic assessment of prosthetic heart valves using conventional 2D transthoracic Echocardiography-Doppler (2D-TTE) has limitations. Of those, left ventricular outflow tract (LVOT) area measurement is one of the major limitations of the continuity equation, which assumes a circular LVOT. (2) Methods: This study comprised 258 patients with severe aortic stenosis (AS), who were treated with the ACURATE neo2. The LVOT area and its dependent Doppler-derived parameters, including effective orifice area (EOA) and stroke volume (SV), in addition to their indexed values, were calculated from post-TAVI 2D-TTE. In addition, the 3D-LVOT area from pre-procedural MDCT scans was obtained and used to calculate corrected Doppler-derived parameters. The incidence rates of prosthesis patient mismatch (PPM) were compared between the 2D-TTE and MDCT-based methods (3) Results: The main results show that the 2D-TTE measured LVOT is significantly smaller than 3D-MDCT (350.4 ± 62.04 mm2 vs. 405.22 ± 81.32 mm2) (95% Credible interval (CrI) of differences: −55.15, −36.09), which resulted in smaller EOA (2.25 ± 0.59 vs. 2.58 ± 0.63 cm2) (Beta = −0.642 (95%CrI of differences: −0.85, −0.43), and lower SV (73.88 ± 21.41 vs. 84.47 ± 22.66 mL), (Beta = −7.29 (95% CrI: −14.45, −0.14)), respectively. PPM incidence appears more frequent with 2D-TTE- than 3D-MDCT-corrected measurements (based on the EOAi) 8.52% vs. 2.32%, respectively. In addition, significant differences regarding the EOA among the three valve sizes (S, M and L) were seen only with the MDCT, but not on 2D-TTE. (4) Conclusions: The corrected continuity equation by combining the 3D-LVOT area from MDCT with the TTE Doppler parameters might provide a more accurate assessment of hemodynamic parameters and PPM diagnosis in patients treated with TAVI. The ACURATE neo2 THV has a large EOA and low incidence of PPM using the 3D-corrected LVOT area than on 2D-TTE. These findings need further confirmation on long-term follow-up and in other studies.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Rück, AndreasKarolinska Institutet,Karolinska University Hospital
(author)
-
Kim, Won KeunMax Planck Institute for Heart and Lung Research
(author)
-
Abdel-Wahab, MohamedLeipzig University
(author)
-
Abdelshafy, MahmoudGalway University Hospital
(author)
-
De Backer, OleCopenhagen University Hospital
(author)
-
Elzomor, HeshamGalway University Hospital
(author)
-
Hengstenberg, ChristianMedical University of Vienna
(author)
-
Mohamed, Sameh K.Galway University Hospital
(author)
-
Saleh, NawzadKarolinska Institutet,Karolinska University Hospital
(author)
-
Arsang-Jang, ShahramGalway University Hospital
(author)
-
Bjursten, HenrikLund University,Lunds universitet,Skonsammare hjärtkirurgi,Forskargrupper vid Lunds universitet,Less invasive cardiac surgery,Lund University Research Groups,Skåne University Hospital(Swepub:lu)thor-hjo
(author)
-
Simpkin, AndrewNational University of Ireland Galway
(author)
-
Meduri, Christopher U.Karolinska University Hospital
(author)
-
Soliman, OsamaGalway University Hospital
(author)
-
Karolinska InstitutetGalway University Hospital
(creator_code:org_t)
Related titles
-
In:Journal of Clinical Medicine: MDPI AG11:20, s. 1-122077-0383
Internet link
Find in a library
To the university's database
- By the author/editor
-
Elkoumy, Ahmed
-
Rück, Andreas
-
Kim, Won Keun
-
Abdel-Wahab, Moh ...
-
Abdelshafy, Mahm ...
-
De Backer, Ole
-
show more...
-
Elzomor, Hesham
-
Hengstenberg, Ch ...
-
Mohamed, Sameh K ...
-
Saleh, Nawzad
-
Arsang-Jang, Sha ...
-
Bjursten, Henrik
-
Simpkin, Andrew
-
Meduri, Christop ...
-
Soliman, Osama
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Radiology Nuclea ...
- Articles in the publication
-
Journal of Clini ...
- By the university
-
Lund University
-
Karolinska Institutet