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Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers
- Ivarsson, K (author)
- Olsrud, J (author)
- Sturesson, C (author)
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- Moller, P. H (author)
- Tranberg, K. G (author)
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- 1998
- 1998
- English.
- In: Lasers in Surgery and Medicine. - 0196-8092. ; 22:2, s. 86-96
- Journal article (peer-reviewed)
Abstract
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- Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on the bioheat equation was used to calculate the temperature distributions. Results: Temperature regulation was excellent with a tendency towards better regulation in the four-fiber than in the single-fiber experiments. Agreement between calculated and measured temperatures was good. The coagulated (>55 degrees C) and hyperthermic (>45 degrees C) volumes were 6 and 10-11 times larger, respectively, with four-fibers than with a single fiber. Conclusion: It is concluded that the stepwise power regulation system was efficient in maintaining a stable target temperature. The results indicate that the system can produce lesion volumes adequate for treating a relatively large tumor in a single session and that computer simulation may be useful for predicting temperature distribution. (C) 1998 Wiley-Liss, Inc.
Subject headings
- NATURVETENSKAP -- Fysik -- Atom- och molekylfysik och optik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Atom and Molecular Physics and Optics (hsv//eng)
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