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Simulation of breas...
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Tomic, HannaLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments
(author)
Simulation of breast lesions based upon fractal Perlin noise
- Article/chapterEnglish2023
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LIBRIS-ID:oai:lup.lub.lu.se:2e60e752-48cf-4a3c-b7c1-f8566c137c87
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https://lup.lub.lu.se/record/2e60e752-48cf-4a3c-b7c1-f8566c137c87URI
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https://doi.org/10.1016/j.ejmp.2023.102681DOI
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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Purpose: Steadily increasing use of computational/virtual phantoms in medical physics has motivated expanding development of new simulation methods and data representations for modelling human anatomy. This has emphasized the need for increased realism, user control, and availability. In breast cancer research, virtual phantoms have gained an important role in evaluating and optimizing imaging systems. For this paper, we have developed an algorithm to model breast abnormalities based on fractal Perlin noise. We demonstrate and characterize the extension of this approach to simulate breast lesions of various sizes, shapes, and complexity. Materials and method: Recently, we developed an algorithm for simulating the 3D arrangement of breast anatomy based on Perlin noise. In this paper, we have expanded the method to also model soft tissue breast lesions. We simulated lesions within the size range of clinically representative breast lesions (masses, 5–20 mm in size). Simulated lesions were blended into simulated breast tissue backgrounds and visualized as virtual digital mammography images. The lesions were evaluated by observers following the BI-RADS assessment criteria. Results: Observers categorized the lesions as round, oval or irregular, with circumscribed, microlobulated, indistinct or obscured margins. The majority of the simulated lesions were considered by the observers to have a realism score of moderate to well. The simulation method provides almost real-time lesion generation (average time and standard deviation: 1.4 ± 1.0 s). Conclusion: We presented a novel algorithm for computer simulation of breast lesions using Perlin noise. The algorithm enables efficient simulation of lesions, with different sizes and appearances.
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Costa, Arthur C.University of São Paulo
(author)
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Bjerkén, AnnaLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Medical Radiation Physics, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)an5554be
(author)
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Vieira, Marcelo A.C.University of São Paulo
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Zackrisson, SophiaLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,LTH profilområde: Avancerade ljuskällor,LTH profilområden,Lunds Tekniska Högskola,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments,LTH Profile Area: Photon Science and Technology,LTH Profile areas,Faculty of Engineering, LTH(Swepub:lu)smi-sza
(author)
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Tingberg, AndersLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Medical Radiation Physics, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)rfa-ati
(author)
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Timberg, PontusLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)po6304ti
(author)
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Dustler, MagnusLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Medical Radiation Physics, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)med-mdu
(author)
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Bakic, Predrag R.Lund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)pr1633ba
(author)
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Diagnostisk radiologi, LundSektion V
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In:Physica Medica1141120-1797
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