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Cervical cytology biobanking in Europe
- Arbyn, Marc (author)
- Van Veen, Evert-Ben (author)
-
- Andersson, Kristin (author)
- Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Epidemiologi,Clinical Microbiology, Malmö,Lund University Research Groups,Epidemiology
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- Bogers, Johannes (author)
- Boulet, Gaelle (author)
- Bergeron, Christine (author)
- von Knebel-Doeberitz, Magnus (author)
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- (creator_code:org_t)
- SAGE Publications, 2010
- 2010
- English.
- In: International Journal of Biological Markers. - : SAGE Publications. - 0393-6155 .- 1724-6008. ; 25:3, s. 117-125
- Journal article (peer-reviewed)
Abstract
Subject headings
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- A cervical cytology biobank (CCB) is an extension of current cytopathology laboratory practice consisting in the systematic storage of Pap smears or liquid-based cytology samples from women participating in cervical cancer screening with the explicit purpose to facilitate future scientific research and quality audit of preventive services. A CCB should use an internationally agreed uniform cytology terminology, be integrated in a national or regional screening registry, and be linked to other registries (histology, cancer, vaccination). Legal and ethical principles concerning personal integrity and data safety must be respected strictly. Biobank-based studies require approval of ethical review boards. A CCB is an almost inexhaustible resource for fundamental and applied biological research. In particular, it can contribute to answering questions on the natural history of HPV infection and HPV-induced lesions and cancers, screening effectiveness, exploration of new biomarkers, and surveillance of the short- and long-term effects of the introduction of HPV vaccination. To understand the limitations of CCB, more studies are needed on the quality of samples in relation to sample type, storage procedures, and duration of storage.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- papillomavirus
- Human
- Molecular markers
- Biobank
- Cervical cancer
- Cervical cytology
Publication and Content Type
- art (subject category)
- ref (subject category)
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