Search: onr:"swepub:oai:lup.lub.lu.se:31a21357-b713-483f-9504-0cf94a8d6ef4" >
Lifestyle changes i...
-
Botteri, EdoardoCancer Registry of Norway, Institute of Population-Based Cancer Research
(author)
Lifestyle changes in middle age and risk of cancer : evidence from the European Prospective Investigation into Cancer and Nutrition
- Article/chapterEnglish2024
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:31a21357-b713-483f-9504-0cf94a8d6ef4
-
https://lup.lub.lu.se/record/31a21357-b713-483f-9504-0cf94a8d6ef4URI
-
https://doi.org/10.1007/s10654-023-01059-4DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:154500117URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index and physical activity. HLI ranged from 0 (most unfavourable) to 16 (most favourable). We estimated the association between HLI change and risk of lifestyle-related cancers—including cancer of the breast, lung, colorectum, stomach, liver, cervix, oesophagus, bladder, and others—using Cox regression models. We reported hazard ratios (HR) with 95% confidence intervals (CI). Median time between the two questionnaires was 5.7 years, median age at follow-up questionnaire was 59 years. After the follow-up questionnaire, we observed 14,933 lifestyle-related cancers over a median follow-up of 7.8 years. Each unit increase in the HLI score was associated with 4% lower risk of lifestyle-related cancers (HR 0.96; 95%CI 0.95–0.97). Among participants in the top HLI third at baseline (HLI > 11), those in the bottom third at follow-up (HLI ≤ 9) had 21% higher risk of lifestyle-related cancers (HR 1.21; 95%CI 1.07–1.37) than those remaining in the top third. Among participants in the bottom HLI third at baseline, those in the top third at follow-up had 25% lower risk of lifestyle-related cancers (HR 0.75; 95%CI 0.65–0.86) than those remaining in the bottom third. These results indicate that lifestyle changes in middle age may have a significant impact on cancer risk.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Peveri, GiuliaKarolinska Institute,University of Milan
(author)
-
Berstad, PaulaCancer Registry of Norway, Institute of Population-Based Cancer Research
(author)
-
Bagnardi, VincenzoUniversity of Milano-Bicocca
(author)
-
Hoff, GeirCancer Registry of Norway, Institute of Population-Based Cancer Research,Telemark Hospital
(author)
-
Heath, Alicia K.Imperial College London
(author)
-
Cross, Amanda J.Imperial College London
(author)
-
Vineis, PaoloImperial College London
(author)
-
Dossus, LaureInternational Agency for Research on Cancer, World Health Organization
(author)
-
Johansson, MattiasInternational Agency for Research on Cancer, World Health Organization
(author)
-
Freisling, HeinzInternational Agency for Research on Cancer, World Health Organization
(author)
-
Matta, KomodoInternational Agency for Research on Cancer, World Health Organization
(author)
-
Huybrechts, IngeInternational Agency for Research on Cancer, World Health Organization
(author)
-
Chen, Sairah L.F.UiT The Arctic University of Norway, Tromsø
(author)
-
B. Borch, KristinUiT The Arctic University of Norway, Tromsø
(author)
-
Sandanger, Torkjel M.UiT The Arctic University of Norway, Tromsø
(author)
-
H. Nøst, ThereseUiT The Arctic University of Norway, Tromsø,Norwegian University of Science and Technology
(author)
-
Dahm, Christina C.Aarhus University
(author)
-
Antoniussen, Christian S.Aarhus University
(author)
-
Tin Tin, SandarUniversity of Oxford
(author)
-
Fournier, AgnèsVersailles Saint-Quentin-en-Yvelines University
(author)
-
Marques, ChloéVersailles Saint-Quentin-en-Yvelines University
(author)
-
Artaud, FannyVersailles Saint-Quentin-en-Yvelines University
(author)
-
Sánchez, Maria JoséAndalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP),University of Granada
(author)
-
Guevara, MarcelaHealth Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP)
(author)
-
Santiuste, CarmenCIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council
(author)
-
Agudo, AntonioCatalan Institute of Oncology,Bellvitge Biomedical Research Institute
(author)
-
Bajracharya, RashmitaGerman Cancer Research Centre
(author)
-
Katzke, VerenaGerman Cancer Research Centre
(author)
-
Ricceri, FulvioUniversity of Turin
(author)
-
Agnoli, ClaudiaIstituto Nazionale dei Tumori
(author)
-
Bergmann, Manuela M.German Institute of Human Nutrition
(author)
-
Schulze, Matthias B.University of Potsdam,German Institute of Human Nutrition
(author)
-
Panico, SalvatoreUniversity of Naples Federico II
(author)
-
Masala, GiovannaInstitute for Cancer Research, Prevention and Clinical Network (ISPRO)
(author)
-
Tjønneland, AnneDanish Cancer Society,University of Copenhagen
(author)
-
Olsen, AnjaDanish Cancer Society,Aarhus University
(author)
-
Stocks, TanjaLund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Registerbaserad epidemiologi - Stocks,Institutionen för translationell medicin,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Register-based epidemiology,Department of Translational Medicine,Faculty of Medicine(Swepub:lu)med-tss
(author)
-
Manjer, JonasLund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Surgery,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)smi-jma
(author)
-
Aizpurua-Atxega, AmaiaBiodonostia Health Research Institute
(author)
-
Weiderpass, ElisabeteInternational Agency for Research on Cancer, World Health Organization
(author)
-
Riboli, ElioImperial College London
(author)
-
Gunter, Marc J.Imperial College London,International Agency for Research on Cancer, World Health Organization
(author)
-
Ferrari, PietroInternational Agency for Research on Cancer, World Health Organization
(author)
-
Karolinska InstituteCancer Registry of Norway, Institute of Population-Based Cancer Research
(creator_code:org_t)
Related titles
-
In:European Journal of Epidemiology39:2, s. 147-1590393-2990
-
In:European journal of epidemiology39:2, s. 147-1591573-7284
Internet link
Find in a library
To the university's database
- By the author/editor
-
Botteri, Edoardo
-
Peveri, Giulia
-
Berstad, Paula
-
Bagnardi, Vincen ...
-
Hoff, Geir
-
Heath, Alicia K.
-
show more...
-
Cross, Amanda J.
-
Vineis, Paolo
-
Dossus, Laure
-
Johansson, Matti ...
-
Freisling, Heinz
-
Matta, Komodo
-
Huybrechts, Inge
-
Chen, Sairah L.F ...
-
B. Borch, Kristi ...
-
Sandanger, Torkj ...
-
H. Nøst, Therese
-
Dahm, Christina ...
-
Antoniussen, Chr ...
-
Tin Tin, Sandar
-
Fournier, Agnès
-
Marques, Chloé
-
Artaud, Fanny
-
Sánchez, Maria J ...
-
Guevara, Marcela
-
Santiuste, Carme ...
-
Agudo, Antonio
-
Bajracharya, Ras ...
-
Katzke, Verena
-
Ricceri, Fulvio
-
Agnoli, Claudia
-
Bergmann, Manuel ...
-
Schulze, Matthia ...
-
Panico, Salvator ...
-
Masala, Giovanna
-
Tjønneland, Anne
-
Olsen, Anja
-
Stocks, Tanja
-
Manjer, Jonas
-
Aizpurua-Atxega, ...
-
Weiderpass, Elis ...
-
Riboli, Elio
-
Gunter, Marc J.
-
Ferrari, Pietro
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
- Articles in the publication
-
European Journal ...
-
European journal ...
- By the university
-
Lund University
-
Karolinska Institutet