In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell

The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism.

Elofsson, RolfLund University,Lunds universitet,Funktionell zoologi,Biologiska institutionen,Naturvetenskapliga fakulteten,Functional zoology,Department of Biology,Faculty of Science(Swepub:lu)zool-rel (author)
Falck, BengtLund University,Lunds universitet,Kansli för experimentell medicinsk vetenskap,Institutionen för experimentell medicinsk vetenskap,Medicinska fakulteten,Department Office of Experimental Medical Science,Department of Experimental Medical Science,Faculty of Medicine(Swepub:lu)mphy-bfa (author)
Sjöborg, SteinarLund University (author)
Funktionell zoologiBiologiska institutionen (creator_code:org_t)

By the author/editor: Axelsson, S; Elofsson, Rolf; Falck, Bengt; Sjöborg, Steinar

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dermatology and ...

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